Pseudomonas aeruginosa PAO1, PA0668 (tyrZ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0004106 chorismate mutase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006568 tryptophan metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0044267 cellular protein metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0043039 tRNA aminoacylation
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0003723 RNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.10.290.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00579
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006437 tyrosyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00234
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004831 tyrosine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00234
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00579
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00579
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00579
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Translation, post-translational modification, degradation Other PAO1 genes in this class
Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Aminoacyl-tRNA biosynthesis ECO:0000037
not_recorded
KEGG pae00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc TRNA-CHARGING-PWY tRNA charging 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCAP Tryptophan metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.10.290.10 - IPR036986 RNA-binding S4 domain superfamily 323 387 6.7E-11
FunFam G3DSA:1.10.240.10:FF:000006 Tyrosine--tRNA ligase - - 219 325 2.9E-45
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 178 200 2.2E-26
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 161 176 2.2E-26
SUPERFAMILY SSF52374 Nucleotidylyl transferase - - 4 310 2.43E-99
Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 2 396 48.201878
Pfam PF00579 tRNA synthetases class I (W and Y) IPR002305 Aminoacyl-tRNA synthetase, class Ic 31 315 9.6E-81
Gene3D G3DSA:1.10.240.10 - - - 219 322 9.8E-37
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 2 218 9.0E-83
PANTHER PTHR11766 TYROSYL-TRNA SYNTHETASE IPR024088 Tyrosine-tRNA ligase, bacterial-type 11 392 1.8E-87
CDD cd00805 TyrRS_core IPR002307 Tyrosine-tRNA ligase 34 298 8.29218E-115
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 211 223 2.2E-26
NCBIfam TIGR00234 JCVI: tyrosine--tRNA ligase IPR002307 Tyrosine-tRNA ligase 2 396 5.3E-119
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 46 68 2.2E-26
SUPERFAMILY SSF55174 Alpha-L RNA-binding motif - - 320 396 9.68E-14
FunFam G3DSA:3.40.50.620:FF:000061 Tyrosine--tRNA ligase - - 2 218 1.6E-124

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.