Pseudomonas aeruginosa PAO1, PA1010 (dapA)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0006520	cellular amino acid metabolic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0009085	lysine biosynthetic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Molecular Function	GO:0003855	3-dehydroquinate dehydratase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0009089	lysine biosynthetic process via diaminopimelate	ISM Inferred from Sequence Model Term mapped from: InterPro:cd00950	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016829	lyase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR12128	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0008840	4-hydroxy-tetrahydrodipicolinate synthase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:cd00950	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae01110	Biosynthesis of secondary metabolites	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01120	Microbial metabolism in diverse environments	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Lysine biosynthesis		ECO:0000037 not_recorded
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01230	Biosynthesis of amino acids	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01130	Biosynthesis of antibiotics	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00300	Lysine biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	P4-PWY	superpathway of L-lysine, L-threonine and L-methionine biosynthesis I	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae00261	Monobactam biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	DAPLYSINESYN-PWY	L-lysine biosynthesis I	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Coils	Coil	Coil	-	-	160	180	-
SMART	SM01130	DHDPS_2	IPR002220	DapA-like	1	289	0.0
PIRSF	PIRSF001365	DHDPS	IPR002220	DapA-like	1	292	1.9E-100
NCBIfam	TIGR00674	JCVI: 4-hydroxy-tetrahydrodipicolinate synthase	IPR005263	4-hydroxy-tetrahydrodipicolinate synthase, DapA	5	286	3.3E-115
CDD	cd00950	DHDPS	IPR005263	4-hydroxy-tetrahydrodipicolinate synthase, DapA	4	285	0.0
PRINTS	PR00146	Dihydrodipicolinate synthase signature	IPR002220	DapA-like	71	89	8.9E-35
PRINTS	PR00146	Dihydrodipicolinate synthase signature	IPR002220	DapA-like	128	145	8.9E-35
Hamap	MF_00418	4-hydroxy-tetrahydrodipicolinate synthase [dapA].	IPR005263	4-hydroxy-tetrahydrodipicolinate synthase, DapA	1	287	69.373184
Pfam	PF00701	Dihydrodipicolinate synthetase family	IPR002220	DapA-like	2	285	1.7E-109
PANTHER	PTHR12128	DIHYDRODIPICOLINATE SYNTHASE	IPR002220	DapA-like	3	290	1.0E-81
PRINTS	PR00146	Dihydrodipicolinate synthase signature	IPR002220	DapA-like	103	119	8.9E-35
PRINTS	PR00146	Dihydrodipicolinate synthase signature	IPR002220	DapA-like	35	56	8.9E-35
Gene3D	G3DSA:3.20.20.70	Aldolase class I	IPR013785	Aldolase-type TIM barrel	1	291	9.8E-111
SUPERFAMILY	SSF51569	Aldolase	-	-	2	289	3.87E-107

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.