Pseudomonas aeruginosa PAO1, PA1246 (aprD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0046903 secretion
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 1427098 Reviewed by curator
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01842
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0030256 type I protein secretion system complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01842
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01842
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00382
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055085 transmembrane transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00664
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0140359 ABC-type transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00664
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0030253 protein secretion by the type I secretion system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01842
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Protein secretion/export apparatus Other PAO1 genes in this class
Secreted Factors (toxins, enzymes, alginate) Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02010 ABC transporters 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Apr type I secretion system ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00382 AAA_5 IPR003593 AAA+ ATPase domain 358 544 2.6E-14
CDD cd18586 ABC_6TM_PrtD_like IPR047957 Alkaline protease secretion ATP-binding protein AprD-like, 6TM domain 20 309 7.97908E-115
Pfam PF00664 ABC transporter transmembrane region IPR011527 ABC transporter type 1, transmembrane domain 34 282 2.2E-12
SUPERFAMILY SSF90123 ABC transporter transmembrane region IPR036640 ABC transporter type 1, transmembrane domain superfamily 19 320 5.76E-45
Gene3D G3DSA:1.20.1560.10 ABC transporter type 1, transmembrane domain IPR036640 ABC transporter type 1, transmembrane domain superfamily 14 315 2.9E-31
PANTHER PTHR24221 ATP-BINDING CASSETTE SUB-FAMILY B IPR039421 Type 1 protein exporter 27 556 6.7E-73
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 322 556 1.84E-62
FunFam G3DSA:3.40.50.300:FF:001444 ABC transporter ATP-binding protein - - 327 559 8.7E-101
Pfam PF00005 ABC transporter IPR003439 ABC transporter-like, ATP-binding domain 349 496 1.9E-28
NCBIfam TIGR01842 JCVI: type I secretion system permease/ATPase IPR010128 ATPase, type I secretion system, PrtD-like 16 558 0.0
FunFam G3DSA:1.20.1560.10:FF:000109 Alkaline protease secretion ATP-binding protein aprD - - 12 316 0.0
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 334 571 2.2E-70

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.