Pseudomonas aeruginosa PAO1, PA1589 (sucD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009142 nucleoside triphosphate biosynthetic process
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 10671455 Reviewed by curator
Molecular Function GO:0004550 nucleoside diphosphate kinase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 10671455 Reviewed by curator
Molecular Function GO:0004775 succinate-CoA ligase (ADP-forming) activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 10671455 Reviewed by curator
Cellular Component GO:0042709 succinate-CoA ligase complex
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 10671455 Reviewed by curator
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF001553
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Energy metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCyc TCA TCA cycle I (prokaryotic) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00640 Propanoate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc GLYCOLYSIS-TCA-GLYOX-BYPASS superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00660 C5-Branched dibasic acid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc GLUTAMOLYSIS-PWY glutamate degradation III 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCAP Citrate cycle (TCA cycle) ECO:0000037
not_recorded
KEGG pae00020 Citrate cycle (TCA cycle) 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc P22-PWY acetyl-CoA assimilation 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc TCA-GLYOX-BYPASS superpathway of glyoxylate bypass and TCA 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP C5-Branched dibasic acid metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR11117 SUCCINYL-COA LIGASE SUBUNIT ALPHA - - 3 287 0.0
PRINTS PR01798 Succinyl-CoA synthase signature - - 177 195 5.1E-39
FunFam G3DSA:3.40.50.720:FF:000002 Succinate--CoA ligase [ADP-forming] subunit alpha - - 1 120 3.0E-60
PRINTS PR01798 Succinyl-CoA synthase signature - - 240 257 5.1E-39
PIRSF PIRSF001553 SucCS_alpha IPR005810 Succinyl-CoA ligase, alpha subunit 1 290 0.0
PRINTS PR01798 Succinyl-CoA synthase signature - - 208 221 5.1E-39
NCBIfam TIGR01019 JCVI: succinate--CoA ligase subunit alpha IPR005810 Succinyl-CoA ligase, alpha subunit 4 287 0.0
FunFam G3DSA:3.40.50.261:FF:000002 Succinate--CoA ligase [ADP-forming] subunit alpha - - 120 290 3.6E-102
SMART SM00881 CoA_binding_2 IPR003781 CoA-binding 4 100 1.5E-36
Gene3D G3DSA:3.40.50.720 - - - 1 119 3.5E-56
SUPERFAMILY SSF52210 Succinyl-CoA synthetase domains IPR016102 Succinyl-CoA synthetase-like 123 289 1.16E-57
Pfam PF00549 CoA-ligase IPR005811 ATP-citrate lyase/succinyl-CoA ligase 151 270 6.5E-22
Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. IPR005810 Succinyl-CoA ligase, alpha subunit 1 288 42.831444
PRINTS PR01798 Succinyl-CoA synthase signature - - 82 99 5.1E-39
Gene3D G3DSA:3.40.50.261 - IPR016102 Succinyl-CoA synthetase-like 120 293 1.0E-77
Pfam PF02629 CoA binding domain IPR003781 CoA-binding 6 99 2.3E-31
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 1 122 1.93E-42

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.