Pseudomonas aeruginosa PAO1, PA1611

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000155 phosphorelay sensor kinase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 16182517 Reviewed by curator
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00448
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00082
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00082
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00304
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Chemotaxis Other PAO1 genes in this class
Cell wall / LPS / capsule Other PAO1 genes in this class
Two-component regulatory systems Other PAO1 genes in this class
Transcriptional regulators Other PAO1 genes in this class
Motility & Attachment Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Two-component System ECO:0000037
not_recorded
KEGG pae02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:6.10.340.10 - - - 155 249 6.6E-12
CDD cd06225 HAMP - - 194 238 1.02302E-6
SUPERFAMILY SSF158472 HAMP domain-like - - 192 239 3.14E-6
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 516 633 2.28E-39
CDD cd17546 REC_hyHK_CKI1_RcsC-like - - 517 628 1.83766E-53
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 265 330 1.3E-23
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 437 447 1.7E-17
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 252 330 4.32E-22
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 478 491 1.7E-17
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 263 326 2.56306E-16
FunFam G3DSA:3.30.565.10:FF:000010 Sensor histidine kinase RcsC - - 329 496 3.3E-50
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 378 494 7.5E-40
SMART SM00304 HAMP_11 IPR003660 HAMP domain 191 243 1.2E-7
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 454 472 1.7E-17
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 515 628 3.5E-37
FunFam G3DSA:1.10.287.130:FF:000002 Two-component osmosensing histidine kinase - - 252 331 2.1E-28
Pfam PF09984 Single cache domain 4 IPR019247 Histidine kinase BarA, N-terminal 35 101 4.4E-9
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 319 494 6.42E-47
Coils Coil Coil - - 238 265 -
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 331 498 3.2E-50
Gene3D G3DSA:3.40.50.2300 - - - 515 649 8.1E-49
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 265 330 2.4E-19
Pfam PF00672 HAMP domain IPR003660 HAMP domain 188 238 2.7E-9
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 378 492 1.6E-28
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 517 628 1.8E-27
Gene3D G3DSA:1.10.287.130 - - - 252 330 4.9E-26
PANTHER PTHR45339 HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J - - 234 501 0.0
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 419 433 1.7E-17
CDD cd16922 HATPase_EvgS-ArcB-TorS-like - - 383 492 2.59448E-55

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.