Pseudomonas aeruginosa PAO1, PA1780 (nirD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008720 D-lactate dehydrogenase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0008152 metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006807 nitrogen compound metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006783 heme biosynthetic process
IMP
Inferred from Mutant Phenotype 		ECO:0000016
loss-of-function mutant phenotype evidence		 8982003 Reviewed by curator
Molecular Function GO:0008942 nitrite reductase [NAD(P)H] activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF13806
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051537 2 iron, 2 sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50022
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Central intermediary metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00910 Nitrogen metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Nitrogen metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR02378 JCVI: nitrite reductase small subunit NirD IPR012748 Rieske-like [2Fe-2S] domain, NirD-type 2 99 6.1E-32
FunFam G3DSA:2.102.10.10:FF:000013 Nitrite reductase [NAD(P)H], small subunit - - 1 100 1.1E-42
CDD cd03530 Rieske_NirD_small_Bacillus - - 3 100 1.48177E-56
Gene3D G3DSA:2.102.10.10 - IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily 1 100 2.4E-27
PANTHER PTHR21496 FERREDOXIN-RELATED - - 2 104 2.0E-17
SUPERFAMILY SSF50022 ISP domain IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily 1 103 1.7E-34
Pfam PF13806 Rieske-like [2Fe-2S] domain IPR012748 Rieske-like [2Fe-2S] domain, NirD-type 2 98 3.6E-15

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.