Pseudomonas aeruginosa PAO1, PA2025 (gor)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0006749	glutathione metabolic process	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0051188	obsolete cofactor biosynthetic process	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0006520	cellular amino acid metabolic process	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0006536	glutamate metabolic process	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0045454	cell redox homeostasis	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR42737	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016491	oxidoreductase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:G3DSA:3.30.390.30	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR42737	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCAP		Glutathione metabolism		ECO:0000037 not_recorded
PseudoCAP		Glutamate metabolism		ECO:0000037 not_recorded
PseudoCyc	GLUT-REDOX-PWY	glutathione redox reactions II	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae00480	Glutathione metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PANTHER	PTHR42737	GLUTATHIONE REDUCTASE	IPR046952	Glutathione reductase/thioredoxin reductase-like	4	448	0.0
FunFam	G3DSA:3.50.50.60:FF:000051	Glutathione reductase	-	-	151	270	1.4E-44
PRINTS	PR00368	FAD-dependent pyridine nucleotide reductase signature	-	-	168	186	5.3E-30
Pfam	PF02852	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	IPR004099	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	338	446	2.0E-35
SUPERFAMILY	SSF55424	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	IPR016156	FAD/NAD-linked reductase, dimerisation domain superfamily	335	447	3.95E-36
PRINTS	PR00411	Pyridine nucleotide disulphide reductase class-I signature	-	-	168	193	1.8E-68
PIRSF	PIRSF000350	Hg-II_reductase_MerA	IPR001100	Pyridine nucleotide-disulphide oxidoreductase, class I	1	444	1.2E-86
Pfam	PF07992	Pyridine nucleotide-disulphide oxidoreductase	IPR023753	FAD/NAD(P)-binding domain	6	317	1.6E-68
PRINTS	PR00411	Pyridine nucleotide disulphide reductase class-I signature	-	-	421	441	1.8E-68
PRINTS	PR00411	Pyridine nucleotide disulphide reductase class-I signature	-	-	6	28	1.8E-68
PRINTS	PR00368	FAD-dependent pyridine nucleotide reductase signature	-	-	131	149	5.3E-30
SUPERFAMILY	SSF51905	FAD/NAD(P)-binding domain	IPR036188	FAD/NAD(P)-binding domain superfamily	1	358	8.37E-60
PRINTS	PR00411	Pyridine nucleotide disulphide reductase class-I signature	-	-	399	414	1.8E-68
PRINTS	PR00411	Pyridine nucleotide disulphide reductase class-I signature	-	-	38	53	1.8E-68
PRINTS	PR00368	FAD-dependent pyridine nucleotide reductase signature	-	-	253	269	5.3E-30
PRINTS	PR00411	Pyridine nucleotide disulphide reductase class-I signature	-	-	134	143	1.8E-68
PRINTS	PR00411	Pyridine nucleotide disulphide reductase class-I signature	-	-	254	268	1.8E-68
Gene3D	G3DSA:3.50.50.60	-	IPR036188	FAD/NAD(P)-binding domain superfamily	143	260	3.3E-114
PRINTS	PR00368	FAD-dependent pyridine nucleotide reductase signature	-	-	7	26	5.3E-30
PRINTS	PR00368	FAD-dependent pyridine nucleotide reductase signature	-	-	282	304	5.3E-30
Gene3D	G3DSA:3.30.390.30	-	IPR016156	FAD/NAD-linked reductase, dimerisation domain superfamily	337	451	1.6E-45
PRINTS	PR00411	Pyridine nucleotide disulphide reductase class-I signature	-	-	334	355	1.8E-68
Gene3D	G3DSA:3.50.50.60	-	IPR036188	FAD/NAD(P)-binding domain superfamily	5	319	3.3E-114
PRINTS	PR00411	Pyridine nucleotide disulphide reductase class-I signature	-	-	297	304	1.8E-68

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.