Pseudomonas aeruginosa PAO1, PA2080 (kynU)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0019441 tryptophan catabolic process to kynurenine
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 17337571 Reviewed by curator
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01814
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030170 pyridoxal phosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01814
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006569 tryptophan catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01814
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009435 NAD biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01814
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030429 kynureninase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01814
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Aromatic compound catabolism ECO:0000037
not_recorded
PseudoCAP kynurenine pathway ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00380 Tryptophan metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase, domain 1 IPR015422 Pyridoxal phosphate-dependent transferase, small domain 10 399 0.0
SUPERFAMILY SSF53383 PLP-dependent transferases IPR015424 Pyridoxal phosphate-dependent transferase 3 400 2.45E-92
FunFam G3DSA:3.40.640.10:FF:000107 Kynureninase - - 41 301 0.0
PANTHER PTHR14084 KYNURENINASE IPR010111 Kynureninase 7 404 1.4E-98
Gene3D G3DSA:3.40.640.10 - IPR015421 Pyridoxal phosphate-dependent transferase, major domain 41 301 0.0
PIRSF PIRSF038800 KYNU IPR010111 Kynureninase 1 407 0.0
Hamap MF_01970 Kynureninase [kynU]. IPR010111 Kynureninase 1 399 35.183388
NCBIfam TIGR01814 JCVI: kynureninase IPR010111 Kynureninase 8 399 8.0E-103
Pfam PF00266 Aminotransferase class-V IPR000192 Aminotransferase class V domain 77 363 2.9E-16

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.