Pseudomonas aeruginosa PAO1, PA2138 (ligD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016779 nucleotidyltransferase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 15520014 Reviewed by curator
Molecular Function GO:0003910 DNA ligase (ATP) activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 15520014 Reviewed by curator
Molecular Function GO:0003887 DNA-directed DNA polymerase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 15520014 Reviewed by curator
Molecular Function GO:0004532 exoribonuclease activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 15897197 Reviewed by curator
Biological Process GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 15897197 Reviewed by curator
Biological Process GO:0071897 DNA biosynthetic process
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 15520014 Reviewed by curator
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01068
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003910 DNA ligase (ATP) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01068
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006310 DNA recombination
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01068
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01068
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae03450 Non-homologous end-joining 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR02776 JCVI: DNA ligase D IPR014143 DNA ligase D 228 823 0.0
Gene3D G3DSA:3.30.1490.70 - - - 229 397 1.2E-46
MobiDBLite mobidb-lite consensus disorder prediction - - 514 546 -
MobiDBLite mobidb-lite consensus disorder prediction - - 189 211 -
CDD cd04862 PaeLigD_Pol_like IPR033651 LigD polymerase domain, PaeLigD-type 566 792 1.18596E-126
Gene3D G3DSA:3.30.470.30 DNA ligase/mRNA capping enzyme - - 241 356 1.2E-46
Pfam PF01068 ATP dependent DNA ligase domain IPR012310 DNA ligase, ATP-dependent, central 224 399 1.9E-22
MobiDBLite mobidb-lite consensus disorder prediction - - 8 32 -
PANTHER PTHR42705 BIFUNCTIONAL NON-HOMOLOGOUS END JOINING PROTEIN LIGD - - 228 836 3.6E-111
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 403 523 3.98E-28
CDD cd07906 Adenylation_DNA_ligase_LigD_LigC - - 217 400 8.28624E-80
NCBIfam TIGR02779 JCVI: non-homologous end-joining DNA ligase, ligase domain IPR014146 DNA ligase D, ligase domain 219 521 2.2E-110
NCBIfam TIGR02777 JCVI: DNA ligase D, 3'-phosphoesterase domain IPR014144 DNA ligase D, 3'-phosphoesterase domain 7 162 1.5E-70
CDD cd07971 OBF_DNA_ligase_LigD - - 403 520 1.96759E-49
NCBIfam TIGR02778 JCVI: non-homologous end-joining DNA ligase, polymerase domain IPR014145 DNA ligase D, polymerase domain 549 793 2.7E-88
Gene3D G3DSA:3.90.920.10 DNA primase, PRIM domain - - 556 840 2.7E-92
SUPERFAMILY SSF56091 DNA ligase/mRNA capping enzyme, catalytic domain - - 216 399 2.3E-45
Pfam PF04679 ATP dependent DNA ligase C terminal region IPR012309 DNA ligase, ATP-dependent, C-terminal 418 515 1.2E-23
MobiDBLite mobidb-lite consensus disorder prediction - - 1 32 -
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 402 523 8.1E-37
Pfam PF13298 DNA polymerase Ligase (LigD) IPR014144 DNA ligase D, 3'-phosphoesterase domain 40 144 5.1E-39

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.