Pseudomonas aeruginosa PAO1, PA2231 (pslA)

Annotation Updates

Date	Description	Acknowledgements
Jul 29, 2010	New pathway: Psl exopolysaccharide biosynthesis. New GO accession: GO:0042710 [IDA]. New evidence reference (PMID): 19325879. New evidence reference (PMID): 19659934.	Daniel Wozniak, Wake Forest University Health Sciences, USA
Nov 9, 2004	Annotation of gene previously described as probable glycosyl transferase (Class 3) with 56% similarity to putative colanic acid biosynthsis UDP-glucose lipid carrier transferase WcaJ [Escherichia coli]. New evidence references (PubMed ID): 15231776;15231778. New comment: PA2231 and PA2232 play a role in biofilm initiation. psl cluster plays a role in cell-cell and/or cell-surface interaction in biofilm formation. New genomic context: part of pslABCDEFGHIJKLMNO cluster involved in biofilm development. Homology updated: 69% similar to colonic acid UDP-glucose lipid carrier, WcaJ[E. coli].	Raymond C. Lo and Fiona S.L. Brinkman, Simon Fraser University, Canada (based on literature review);
Jun 10, 2004	Annotation of gene previously described as probable glycosyl transferase (Class 3). New gene name: pslA. New evidence reference: Friedman, Lisa, Kolter, Roberto Two genetic loci produce distinct carbohydrate-rich structural components of the Pseudomonas aeruginosa biofilm matrix.. Journal of Bacteriology (in-press). New genomic context: Part of pslABCDEFGHIJK cluster involved in biofilm matrix formation in P. aeruginosa ZK2870.	Lisa C. Friedman and Roberto G. Kolter, Harvard Medical School, USA
Jan 10, 2008	New product name: PslA (Existing value: probable glycosyl transferase). Deleting product name: probable glycosyl transferase. New product name confidence: Class 1 (Existing value: Class 3). New PseudoCAP function class: Cell wall / LPS / capsule. New evidence reference (PMID): 15231778. New evidence reference (PMID): 16085831.	Joerg Overhage, University of British Columbia, Canada