Pseudomonas aeruginosa PAO1, PA2523 (czcR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:1900233 positive regulation of single-species biofilm formation on inanimate substrate
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
22666466 Reviewed by curator
Molecular Function GO:0000156 phosphorelay response regulator activity
ISS
Inferred from Sequence or Structural Similarity
ECO:0000250
sequence similarity evidence used in manual assertion
10570969 Reviewed by curator
Biological Process GO:0043902 positive regulation of multi-organism process
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
22666466 Reviewed by curator
Biological Process GO:0032411 positive regulation of transporter activity
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
14679195 Reviewed by curator
Biological Process GO:0045862 positive regulation of proteolysis
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
22666466 Reviewed by curator
Biological Process GO:1900377 negative regulation of secondary metabolite biosynthetic process
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
22666466 Reviewed by curator
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00383
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00383
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00383
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PAO1 genes in this class
Transcriptional regulators Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Two-component System ECO:0000037
not_recorded
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR48111 REGULATOR OF RPOS IPR039420 Transcriptional regulatory protein WalR-like 1 222 1.0E-56
CDD cd00383 trans_reg_C IPR001867 OmpR/PhoB-type DNA-binding domain 132 220 4.11401E-31
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 1 111 8.1E-40
SUPERFAMILY SSF46894 C-terminal effector domain of the bipartite response regulators IPR016032 Signal transduction response regulator, C-terminal effector 124 221 2.04E-28
CDD cd19935 REC_OmpR_CusR-like - - 3 101 6.60509E-53
Gene3D G3DSA:1.10.10.10 - IPR036388 Winged helix-like DNA-binding domain superfamily 117 224 1.6E-30
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 1 121 6.12E-38
FunFam G3DSA:1.10.10.10:FF:000005 Two-component system response regulator - - 121 223 1.1E-35
NCBIfam TIGR01387 JCVI: heavy metal response regulator transcription factor IPR006291 Transcriptional regulatory protein CusR-like, heavy metal response 3 220 4.1E-101
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 3 112 2.3E-26
Pfam PF00486 Transcriptional regulatory protein, C terminal IPR001867 OmpR/PhoB-type DNA-binding domain 148 220 2.6E-25
Gene3D G3DSA:3.40.50.2300 - - - 1 86 4.2E-19
SMART SM00862 Trans_reg_C_3 IPR001867 OmpR/PhoB-type DNA-binding domain 145 220 6.0E-23
Gene3D G3DSA:6.10.250.690 - - - 87 116 4.4E-16
FunFam G3DSA:3.40.50.2300:FF:000001 DNA-binding response regulator PhoB - - 1 79 3.6E-24

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.