Pseudomonas aeruginosa PAO1, PA2967 (fabG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0044255 cellular lipid metabolic process
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Molecular Function GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
IGI
Inferred from Genetic Interaction
ECO:0000012
functional complementation evidence
10781572 Reviewed by curator
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01830
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01830
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006633 fatty acid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01830
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Fatty acid and phospholipid metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00780 Biotin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00061 Fatty acid biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01212 Fatty acid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01040 Biosynthesis of unsaturated fatty acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.40.50.720:FF:000037 3-oxoacyl-[acyl-carrier-protein] reductase FabG - - 1 247 1.1E-127
PRINTS PR00081 Glucose/ribitol dehydrogenase family signature IPR002347 Short-chain dehydrogenase/reductase SDR 128 144 3.6E-46
PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature IPR002347 Short-chain dehydrogenase/reductase SDR 154 173 3.3E-12
NCBIfam TIGR01830 JCVI: 3-oxoacyl-[acyl-carrier-protein] reductase IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase 8 245 3.9E-100
PRINTS PR00081 Glucose/ribitol dehydrogenase family signature IPR002347 Short-chain dehydrogenase/reductase SDR 154 173 3.6E-46
PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature IPR002347 Short-chain dehydrogenase/reductase SDR 81 92 3.3E-12
PRINTS PR00081 Glucose/ribitol dehydrogenase family signature IPR002347 Short-chain dehydrogenase/reductase SDR 81 92 3.6E-46
Gene3D G3DSA:3.40.50.720 - - - 1 247 4.8E-87
PRINTS PR00081 Glucose/ribitol dehydrogenase family signature IPR002347 Short-chain dehydrogenase/reductase SDR 7 24 3.6E-46
PANTHER PTHR42879 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE - - 1 245 5.1E-85
PRINTS PR00081 Glucose/ribitol dehydrogenase family signature IPR002347 Short-chain dehydrogenase/reductase SDR 208 228 3.6E-46
PRINTS PR00081 Glucose/ribitol dehydrogenase family signature IPR002347 Short-chain dehydrogenase/reductase SDR 175 192 3.6E-46
SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. - - 6 185 1.3E-5
PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature IPR002347 Short-chain dehydrogenase/reductase SDR 134 142 3.3E-12
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 4 246 6.59E-83
CDD cd05333 BKR_SDR_c - - 6 245 7.55475E-125
Pfam PF13561 Enoyl-(Acyl carrier protein) reductase - - 12 244 2.9E-63

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.