Pseudomonas aeruginosa PAO1, PA3044 (rocsS2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 15659157 Reviewed by curator
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01627
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Two-component System ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 636 736 2.1E-5
Gene3D G3DSA:1.10.287.130 - - - 237 313 1.6E-20
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 498 614 8.4E-30
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 361 473 2.2E-29
Gene3D G3DSA:3.30.450.20 PAS domain - - 125 236 8.7E-13
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 303 471 4.85E-44
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 497 658 5.91E-32
CDD cd16922 HATPase_EvgS-ArcB-TorS-like - - 365 473 2.21261E-53
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 435 453 1.0E-15
CDD cd17546 REC_hyHK_CKI1_RcsC-like - - 500 614 7.60211E-40
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 625 736 5.59E-19
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 230 314 1.12E-18
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 248 313 1.8E-14
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 99 225 3.49E-12
Gene3D G3DSA:3.40.50.2300 - - - 486 618 5.3E-32
Pfam PF08448 PAS fold IPR013656 PAS fold-4 119 229 7.0E-9
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 247 313 3.6E-18
FunFam G3DSA:3.30.565.10:FF:000010 Sensor histidine kinase RcsC - - 312 476 7.0E-48
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 658 733 3.31061E-9
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 459 472 1.0E-15
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 245 309 2.93009E-13
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 628 740 6.8E-17
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 647 730 2.8E-13
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 500 614 6.5E-24
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 401 415 1.0E-15
Coils Coil Coil - - 224 247 -
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 360 475 2.1E-37
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 419 429 1.0E-15
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 314 476 1.8E-47
PANTHER PTHR43047 TWO-COMPONENT HISTIDINE PROTEIN KINASE - - 95 616 6.7E-126

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.