Pseudomonas aeruginosa PAO1, PA3152 (hisH2)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0009243	O antigen biosynthetic process	EXP Inferred from Experiment	ECO:0000269 experimental evidence used in manual assertion	18621892	Reviewed by curator
Biological Process	GO:0006547	histidine metabolic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0006520	cellular amino acid metabolic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0000105	histidine biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:PIRSF000495	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016763	transferase activity, transferring pentosyl groups	ISM Inferred from Sequence Model Term mapped from: InterPro:PIRSF000495	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae01110	Biosynthesis of secondary metabolites	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Histidine metabolism		ECO:0000037 not_recorded
PseudoCyc	PWY-7221	guanosine ribonucleotides de novo biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae00340	Histidine metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
MetaCyc		glutaminyl-tRNA<sup>gln</sup> biosynthesis via transamidation	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01230	Biosynthesis of amino acids	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Hamap	MF_00278	Imidazole glycerol phosphate synthase subunit HisH [hisH].	IPR010139	Imidazole glycerol phosphate synthase, subunit H	1	201	34.962563
Pfam	PF00117	Glutamine amidotransferase class-I	IPR017926	Glutamine amidotransferase	3	198	7.2E-19
SUPERFAMILY	SSF52317	Class I glutamine amidotransferase-like	IPR029062	Class I glutamine amidotransferase-like	2	201	3.15E-52
NCBIfam	TIGR01855	JCVI: imidazole glycerol phosphate synthase subunit HisH	IPR010139	Imidazole glycerol phosphate synthase, subunit H	2	200	8.9E-81
Gene3D	G3DSA:3.40.50.880	-	IPR029062	Class I glutamine amidotransferase-like	1	202	1.4E-74
PANTHER	PTHR42701	IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISH	IPR010139	Imidazole glycerol phosphate synthase, subunit H	2	200	3.5E-68
CDD	cd01748	GATase1_IGP_Synthase	IPR010139	Imidazole glycerol phosphate synthase, subunit H	2	199	4.19347E-112
PIRSF	PIRSF000495	Amidotransf_HisH	IPR010139	Imidazole glycerol phosphate synthase, subunit H	1	202	4.5E-75

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.