Pseudomonas aeruginosa PAO1, PA3165 (hisC2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0000105 histidine biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
ECO:0000250
sequence similarity evidence used in manual assertion
22232166 Reviewed by curator
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity
ECO:0000044
sequence similarity evidence
Molecular Function GO:0004400 histidinol-phosphate transaminase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01023
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016740 transferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00599
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009058 biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00155
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008152 metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00599
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.1150.10
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030170 pyridoxal phosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00155
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000105 histidine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01023
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00350 Tyrosine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00401 Novobiocin biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Phenylalanine metabolism ECO:0000037
not_recorded
PseudoCAP Phenylalanine, tyrosine and tryptophan biosynthesis ECO:0000037
not_recorded
KEGG (InterPro) 00360 Phenylalanine metabolism InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00400 Phenylalanine, tyrosine and tryptophan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
UniPathway UPA00031 L-histidine biosynthesis InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
PseudoCAP Histidine metabolism ECO:0000037
not_recorded
KEGG (InterPro) 00400 Phenylalanine, tyrosine and tryptophan biosynthesis InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00350 Tyrosine metabolism InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae00340 Histidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00960 Tropane, piperidine and pyridine alkaloid biosynthesis InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae00360 Phenylalanine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00340 Histidine metabolism InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00401 Novobiocin biosynthesis InterPro 5.8-49.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
PseudoCyc BSUBPHENYLSYN-PWY phenylalanine biosynthesis, Bacillus subtilis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00155 Aminotransferase class I and II IPR004839 Aminotransferase, class I/classII 38 362 3.2E-50
TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase IPR005861 Histidinol-phosphate aminotransferase family 10 364 6.3E-117
SUPERFAMILY SSF53383 IPR015424 Pyridoxal phosphate-dependent transferase 17 366 4.31E-81
Gene3D G3DSA:3.40.640.10 IPR015421 Pyridoxal phosphate-dependent transferase, major domain 50 274 2.0E-118
Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. IPR005861 Histidinol-phosphate aminotransferase family 7 366 62.802
CDD cd00609 AAT_like 39 364 2.05307E-61
ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site 226 235 -
Gene3D G3DSA:3.90.1150.10 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 275 360 2.0E-118
Gene3D G3DSA:3.90.1150.10 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 26 49 2.0E-118

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.