Pseudomonas aeruginosa PAO1, PA3166 (pheA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0006520 | cellular amino acid metabolic process | Inferred from Sequence or Structural Similarity | ECO:0000044 sequence similarity evidence |
||
| Biological Process | GO:0009094 | L-phenylalanine biosynthetic process | Inferred from Sequence or Structural Similarity | ECO:0000250 sequence similarity evidence used in manual assertion |
1919506 | Reviewed by curator |
| Cellular Component | GO:0005737 | cytoplasm |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01807
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0009094 | L-phenylalanine biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01807
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004106 | chorismate mutase activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01807
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004664 | prephenate dehydratase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PF00800
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0046417 | chorismate metabolic process |
Inferred from Sequence Model
Term mapped from: InterPro:SM00830
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
|
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| PseudoCAP | Phenylalanine, tyrosine and tryptophan biosynthesis |
ECO:0000037
not_recorded |
|||
| PseudoCyc | BSUBPHENYLSYN-PWY | phenylalanine biosynthesis, Bacillus subtilis | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| KEGG | pae01230 | Biosynthesis of amino acids | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pae01100 | Metabolic pathways | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pae01110 | Biosynthesis of secondary metabolites | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| PseudoCyc | TYRSYN | L-tyrosine biosynthesis I | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCyc | ALL-CHORISMATE-PWY | superpathway of chorismate metabolism | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCyc | PHESYN | L-phenylalanine biosynthesis I | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCyc | COMPLETE-ARO-PWY | superpathway of aromatic amino acid biosynthesis | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| KEGG | pae00400 | Phenylalanine, tyrosine and tryptophan biosynthesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pae01130 | Biosynthesis of antibiotics | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| PIRSF | PIRSF001500 | Chor_mut_pdt_Ppr | IPR008242 | Bifunctional P-protein, chorismate mutase/prephenate dehydratase | 1 | 365 | 0.0 |
| PANTHER | PTHR21022 | PREPHENATE DEHYDRATASE P PROTEIN | - | - | 76 | 361 | 3.3E-80 |
| SUPERFAMILY | SSF53850 | Periplasmic binding protein-like II | - | - | 96 | 281 | 1.19E-60 |
| Gene3D | G3DSA:3.40.190.10 | - | - | - | 99 | 270 | 1.5E-58 |
| CDD | cd04905 | ACT_CM-PDT | - | - | 282 | 361 | 6.00142E-39 |
| Pfam | PF01817 | Chorismate mutase type II | IPR002701 | Chorismate mutase II, prokaryotic-type | 11 | 93 | 3.2E-22 |
| SUPERFAMILY | SSF55021 | ACT-like | IPR045865 | ACT-like domain | 267 | 362 | 4.93E-28 |
| FunFam | G3DSA:1.20.59.10:FF:000004 | Prephenate dehydratase | - | - | 5 | 96 | 6.0E-37 |
| Pfam | PF00800 | Prephenate dehydratase | IPR001086 | Prephenate dehydratase | 97 | 274 | 1.6E-62 |
| SMART | SM00830 | CM_2_4 | IPR002701 | Chorismate mutase II, prokaryotic-type | 11 | 95 | 1.1E-26 |
| Gene3D | G3DSA:1.20.59.10 | Chorismate mutase | IPR036979 | Chorismate mutase domain superfamily | 4 | 97 | 4.6E-26 |
| Gene3D | G3DSA:3.40.190.10 | - | - | - | 177 | 261 | 1.5E-58 |
| FunFam | G3DSA:3.40.190.10:FF:000029 | Chorismate mutase/Prephenate dehydratase | - | - | 99 | 179 | 3.7E-36 |
| Coils | Coil | Coil | - | - | 7 | 27 | - |
| FunFam | G3DSA:3.40.190.10:FF:000034 | Chorismate mutase/prephenate dehydratase | - | - | 180 | 261 | 2.2E-32 |
| Pfam | PF01842 | ACT domain | IPR002912 | ACT domain | 283 | 348 | 6.5E-11 |
| SUPERFAMILY | SSF48600 | Chorismate mutase II | IPR036263 | Chorismate mutase type II superfamily | 6 | 99 | 2.75E-19 |
| NCBIfam | TIGR01807 | JCVI: chorismate mutase | IPR010957 | Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain | 7 | 85 | 1.8E-31 |
| FunFam | G3DSA:3.30.70.260:FF:000012 | Prephenate dehydratase | - | - | 275 | 365 | 7.6E-35 |
| Gene3D | G3DSA:3.30.70.260 | - | - | - | 275 | 364 | 2.1E-27 |
| CDD | cd13630 | PBP2_PDT_1 | - | - | 94 | 274 | 6.80468E-105 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.