Pseudomonas aeruginosa PAO1, PA3168 (gyrA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006259 DNA metabolic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Molecular Function GO:0004347 glucose-6-phosphate isomerase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Cellular Component GO:0005694 chromosome
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01897
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006259 DNA metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.199.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00187
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00187
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006265 DNA topological change
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00187
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003916 DNA topoisomerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03989
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00187
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Coils Coil Coil - - 500 520 -
SUPERFAMILY SSF56719 Type II DNA topoisomerase IPR013760 DNA topoisomerase, type IIA-like domain superfamily 30 523 0.0
PANTHER PTHR43493 DNA GYRASE/TOPOISOMERASE SUBUNIT A - - 4 887 0.0
Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A IPR002205 DNA topoisomerase, type IIA, domain A 32 507 0.0
SUPERFAMILY SSF101904 GyrA/ParC C-terminal domain-like IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal 534 898 1.7E-99
Gene3D G3DSA:3.30.1360.40 - - - 236 334 0.0
FunFam G3DSA:3.30.1360.40:FF:000002 DNA gyrase subunit A - - 236 334 2.0E-41
Gene3D G3DSA:3.90.199.10 Topoisomerase II, domain 5 IPR013758 DNA topoisomerase, type IIA, domain A, alpha-beta 32 522 0.0
Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat 737 781 1.9E-13
Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat 837 883 2.4E-12
Gene3D G3DSA:2.120.10.90 - IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal 532 885 9.2E-127
SMART SM00434 topIV4 IPR002205 DNA topoisomerase, type IIA, domain A 11 500 0.0
Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat 539 586 1.5E-8
Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat 591 638 1.6E-8
Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat 689 732 2.8E-8
Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat 788 833 2.2E-12
NCBIfam TIGR01063 JCVI: DNA gyrase subunit A - - 8 638 0.0
FunFam G3DSA:3.90.199.10:FF:000001 DNA gyrase subunit A - - 32 251 8.0E-113
MobiDBLite mobidb-lite consensus disorder prediction - - 890 923 -
Hamap MF_01897 DNA gyrase subunit A [gyrA]. IPR005743 DNA gyrase, subunit A 1 885 23.955879
MobiDBLite mobidb-lite consensus disorder prediction - - 881 923 -
CDD cd00187 TOP4c IPR002205 DNA topoisomerase, type IIA, domain A 30 510 0.0
Gene3D G3DSA:1.10.268.10 Topoisomerase, domain 3 IPR013757 DNA topoisomerase, type IIA, alpha-helical domain superfamily 371 493 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.