Pseudomonas aeruginosa PAO1, PA3217 (cyaB)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0006171	cAMP biosynthetic process	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	12586068	Reviewed by curator
Biological Process	GO:0009405	pathogenesis	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	14977975	Reviewed by curator
Molecular Function	GO:0004016	adenylate cyclase activity	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	12586068	Reviewed by curator
Biological Process	GO:0009190	cyclic nucleotide biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00211	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0035556	intracellular signal transduction	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00211	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Putative enzymes Other PAO1 genes in this class Adaptation, Protection Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae00230	Purine metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae02025	Biofilm formation - Pseudomonas aeruginosa	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Type III secretion		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF00211	Adenylate and Guanylate cyclase catalytic domain	IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase	225	408	1.6E-37
SUPERFAMILY	SSF55073	Nucleotide cyclase	IPR029787	Nucleotide cyclase	221	410	1.21E-61
Coils	Coil	Coil	-	-	179	199	-
Coils	Coil	Coil	-	-	440	460	-
Pfam	PF05230	MASE2 domain	IPR007894	MASE2	19	108	1.2E-29
Gene3D	G3DSA:3.30.70.1230	Nucleotide cyclase	IPR029787	Nucleotide cyclase	219	416	1.1E-68
CDD	cd07302	CHD	IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase	228	408	3.82086E-60
FunFam	G3DSA:3.30.70.1230:FF:000025	Adenylate cyclase 1	-	-	219	416	1.6E-127
SMART	SM00044	cyc_6	IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase	188	398	2.0E-34
PANTHER	PTHR43081	ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED	-	-	140	408	5.4E-43

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.