Pseudomonas aeruginosa PAO1, PA3415
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0016746 | transferase activity, transferring acyl groups |
Inferred from Sequence Model
Term mapped from: InterPro:PF00198
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
|
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | pae01110 | Biosynthesis of secondary metabolites | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pae00010 | Glycolysis / Gluconeogenesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| PseudoCyc | LCTACACAT-PWY | lactate oxidation | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| KEGG | pae00020 | Citrate cycle (TCA cycle) | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pae01130 | Biosynthesis of antibiotics | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pae01120 | Microbial metabolism in diverse environments | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pae01200 | Carbon metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pae01100 | Metabolic pathways | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pae00620 | Pyruvate metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Pfam | PF00198 | 2-oxoacid dehydrogenases acyltransferase (catalytic domain) | IPR001078 | 2-oxoacid dehydrogenase acyltransferase, catalytic domain | 163 | 369 | 2.5E-47 |
| FunFam | G3DSA:4.10.320.10:FF:000012 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex | - | - | 113 | 153 | 1.0E-20 |
| Gene3D | G3DSA:4.10.320.10 | - | IPR036625 | E3-binding domain superfamily | 111 | 148 | 6.8E-14 |
| FunFam | G3DSA:2.40.50.100:FF:000079 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex | - | - | 1 | 81 | 6.4E-37 |
| CDD | cd06849 | lipoyl_domain | - | - | 4 | 72 | 2.84697E-28 |
| SUPERFAMILY | SSF51230 | Single hybrid motif | IPR011053 | Single hybrid motif | 2 | 84 | 1.44E-24 |
| PANTHER | PTHR43178 | DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX | - | - | 2 | 369 | 1.9E-80 |
| Pfam | PF02817 | e3 binding domain | IPR004167 | Peripheral subunit-binding domain | 114 | 149 | 2.1E-13 |
| SUPERFAMILY | SSF52777 | CoA-dependent acyltransferases | - | - | 156 | 368 | 6.23E-55 |
| FunFam | G3DSA:3.30.559.10:FF:000029 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex | - | - | 146 | 368 | 6.1E-115 |
| Pfam | PF00364 | Biotin-requiring enzyme | IPR000089 | Biotin/lipoyl attachment | 3 | 73 | 7.9E-19 |
| Gene3D | G3DSA:2.40.50.100 | - | - | - | 1 | 84 | 2.8E-23 |
| Gene3D | G3DSA:3.30.559.10 | - | IPR023213 | Chloramphenicol acetyltransferase-like domain superfamily | 149 | 369 | 3.0E-51 |
| SUPERFAMILY | SSF47005 | Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | IPR036625 | E3-binding domain superfamily | 112 | 153 | 7.85E-10 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.