Pseudomonas aeruginosa PAO1, PA3482 (metG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006555 methionine metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0043039 tRNA aminoacylation
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0044267 cellular protein metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006431 methionyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00399
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF09334
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004825 methionine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00399
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000049 tRNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01588
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF09334
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF09334
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF09334
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Translation, post-translational modification, degradation Other PAO1 genes in this class
Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Aminoacyl-tRNA biosynthesis ECO:0000037
not_recorded
PseudoCAP Methionine metabolism ECO:0000037
not_recorded
KEGG pae00450 Selenocompound metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc TRNA-CHARGING-PWY tRNA charging 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Selenoamino acid metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR45765 METHIONINE--TRNA LIGASE IPR023458 Methionine-tRNA ligase, type 1 3 675 0.0
Gene3D G3DSA:2.20.28.20 - IPR029038 Methionyl-tRNA synthetase, Zn-domain 141 175 0.0
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 41 55 2.2E-24
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 383 394 2.2E-24
NCBIfam TIGR00398 JCVI: methionine--tRNA ligase IPR014758 Methionyl-tRNA synthetase 7 535 0.0
Pfam PF19303 Anticodon binding domain of methionyl tRNA ligase IPR041872 Methionyl-tRNA synthetase, anticodon-binding domain 416 517 3.4E-7
SUPERFAMILY SSF47323 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding 389 547 8.97E-43
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 9 22 2.2E-24
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 89 100 2.2E-24
Pfam PF01588 Putative tRNA binding domain IPR002547 tRNA-binding domain 581 674 3.6E-20
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 7 383 0.0
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 290 305 2.2E-24
FunFam G3DSA:1.10.730.10:FF:000005 Methionine--tRNA ligase - - 388 526 2.3E-57
Gene3D G3DSA:1.10.730.10 - - - 388 526 1.6E-36
NCBIfam TIGR00399 JCVI: methionine--tRNA ligase subunit beta IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal 543 677 7.7E-40
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 570 676 1.64E-26
Pfam PF09334 tRNA synthetases class I (M) IPR015413 Methionyl/Leucyl tRNA synthetase 7 395 0.0
FunFam G3DSA:2.20.28.20:FF:000001 Methionine--tRNA ligase - - 141 175 8.8E-16
CDD cd07957 Anticodon_Ia_Met IPR041872 Methionyl-tRNA synthetase, anticodon-binding domain 373 505 5.86506E-37
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 568 677 1.3E-32
SUPERFAMILY SSF57770 Methionyl-tRNA synthetase (MetRS), Zn-domain IPR029038 Methionyl-tRNA synthetase, Zn-domain 141 175 5.36E-12
CDD cd02800 tRNA_bind_EcMetRS_like IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal 571 677 2.00022E-42
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 250 261 2.2E-24
CDD cd00814 MetRS_core IPR033911 Methioninyl-tRNA synthetase core domain 6 370 0.0
SUPERFAMILY SSF52374 Nucleotidylyl transferase - - 4 386 1.5E-98
Hamap MF_00098 Methionine--tRNA ligase [metG]. IPR023458 Methionine-tRNA ligase, type 1 5 545 39.328537
FunFam G3DSA:2.40.50.140:FF:000042 Methionine--tRNA ligase - - 567 677 8.6E-43

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.