Pseudomonas aeruginosa PAO1, PA3542 (alg44)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	16797016	Reviewed by curator
Biological Process	GO:0042121	alginic acid biosynthetic process	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	16797016	Reviewed by curator
Cellular Component	GO:0009276	Gram-negative-bacterium-type cell wall	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	16797016	Reviewed by curator
Biological Process	GO:0042121	alginic acid biosynthetic process	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	18524915	Reviewed by curator
Biological Process	GO:0044010	single-species biofilm formation	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	16797016	Reviewed by curator
Biological Process	GO:0050896	response to stimulus	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Molecular Function	GO:0035438	cyclic-di-GMP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF07238	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Adaptation, Protection Other PAO1 genes in this class Secreted Factors (toxins, enzymes, alginate) Other PAO1 genes in this class Cell wall / LPS / capsule Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCAP		Alginate biosynthesis		ECO:0000037 not_recorded
KEGG	pae02025	Biofilm formation - Pseudomonas aeruginosa	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00051	Fructose and mannose metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	PWY-6082	alginate biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PANTHER	PTHR30386	MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP	-	-	259	370	2.5E-19
Pfam	PF13437	HlyD family secretion protein	-	-	262	357	1.0E-9
Gene3D	G3DSA:2.40.10.220	predicted glycosyltransferase like domains	-	-	12	122	1.5E-35
Pfam	PF07238	PilZ domain	IPR009875	PilZ domain	16	115	2.2E-11
SUPERFAMILY	SSF141371	PilZ domain-like	-	-	10	124	2.35E-10
Gene3D	G3DSA:2.40.50.100	-	-	-	198	292	3.9E-5

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.