Pseudomonas aeruginosa PAO1, PA3678 (mexL)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0045892	negative regulation of transcription, DNA-templated	IMP Inferred from Mutant Phenotype	ECO:0000016 loss-of-function mutant phenotype evidence	12193619	Reviewed by curator
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA Inferred from Direct Assay	ECO:0000096 electrophoretic mobility shift assay evidence	15855505	Reviewed by curator
Molecular Function	GO:0003677	DNA binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00455	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PANTHER	PTHR30055	HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR	-	-	8	211	1.5E-27
Pfam	PF14246	AefR-like transcriptional repressor, C-terminal domain	IPR039536	Transcriptional regulator TetR, C-terminal, Proteobacteria type	93	209	6.3E-30
Gene3D	G3DSA:1.10.357.10	Tetracycline Repressor, domain 2	-	-	70	211	8.7E-36
SUPERFAMILY	SSF46689	Homeodomain-like	IPR009057	Homeobox-like domain superfamily	12	92	1.5E-17
PRINTS	PR00455	TetR bacterial regulatory protein HTH signature	IPR001647	DNA-binding HTH domain, TetR-type	43	66	2.6E-10
SUPERFAMILY	SSF48498	Tetracyclin repressor-like, C-terminal domain	IPR036271	Tetracyclin repressor-like, C-terminal domain superfamily	91	202	8.16E-11
Pfam	PF00440	Bacterial regulatory proteins, tetR family	IPR001647	DNA-binding HTH domain, TetR-type	22	68	1.3E-16
Gene3D	G3DSA:1.10.10.60	-	-	-	11	67	1.9E-20
FunFam	G3DSA:1.10.10.60:FF:000141	TetR family transcriptional regulator	-	-	15	66	4.4E-23
PRINTS	PR00455	TetR bacterial regulatory protein HTH signature	IPR001647	DNA-binding HTH domain, TetR-type	22	35	2.6E-10

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.