Pseudomonas aeruginosa PAO1, PA3878 (narX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008479 queuine tRNA-ribosyltransferase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006807 nitrogen compound metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006091 generation of precursor metabolites and energy
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0000160 phosphorelay signal transduction system
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07730
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00672
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07730
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00672
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0046983 protein dimerization activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07730
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF003167
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Energy metabolism Other PAO1 genes in this class
Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Nitrogen metabolism ECO:0000037
not_recorded
PseudoCAP Two-component System ECO:0000037
not_recorded
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF07730 Histidine kinase IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain 411 476 5.4E-17
PANTHER PTHR24421 NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED - - 27 613 5.8E-68
CDD cd06225 HAMP - - 195 239 4.14883E-13
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 517 611 1.8E-9
CDD cd16917 HATPase_UhpB-NarQ-NarX-like - - 522 603 4.04567E-27
Gene3D G3DSA:1.20.5.1930 - - - 391 473 1.4E-14
SUPERFAMILY SSF158472 HAMP domain-like - - 193 242 1.06E-9
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 477 610 1.5E-26
Gene3D G3DSA:1.20.120.960 Histidine kinase NarX, sensor domain IPR042295 NarX-like, N-terminal domain superfamily 63 160 5.3E-12
Gene3D G3DSA:6.10.340.10 - - - 161 251 1.7E-14
Coils Coil Coil - - 447 474 -
Pfam PF00672 HAMP domain IPR003660 HAMP domain 192 240 1.7E-13
PIRSF PIRSF003167 HK_NarX/NarQ IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing 17 622 0.0
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 508 608 7.2E-15
SMART SM00304 HAMP_11 IPR003660 HAMP domain 192 244 6.2E-14
Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term IPR029095 NarX-like, N-terminal 62 101 5.0E-7
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 518 608 3.6E-8

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.