Pseudomonas aeruginosa PAO1, PA3974 (ladS)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0016772	transferase activity, transferring phosphorus-containing groups	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0016310	phosphorylation	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0007165	signal transduction	ISM Inferred from Sequence Model Term mapped from: InterPro:cd00082	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0000155	phosphorelay sensor kinase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:cd00082	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0000160	phosphorelay signal transduction system	ISM Inferred from Sequence Model Term mapped from: InterPro:SM00448	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae02025	Biofilm formation - Pseudomonas aeruginosa	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Two-component System		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
SUPERFAMILY	SSF52172	CheY-like	IPR011006	CheY-like superfamily	667	785	1.05E-39
Gene3D	G3DSA:1.10.287.130	-	-	-	383	481	2.4E-19
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	588	598	1.0E-12
SMART	SM00388	HisKA_10	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	418	483	5.3E-16
Pfam	PF07696	7TMR-DISM extracellular 2	IPR011622	7TM-DISM receptor, extracellular domain, type 2	32	171	5.4E-37
Gene3D	G3DSA:3.40.50.2300	-	-	-	669	791	2.5E-47
Gene3D	G3DSA:3.30.565.10	-	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	482	647	4.0E-42
FunFam	G3DSA:3.30.565.10:FF:000010	Sensor histidine kinase RcsC	-	-	482	647	7.0E-45
SUPERFAMILY	SSF47384	Homodimeric domain of signal transducing histidine kinase	IPR036097	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily	404	484	1.12E-16
Gene3D	G3DSA:2.60.40.2380	-	-	-	29	178	3.6E-38
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	629	642	1.0E-12
Pfam	PF00072	Response regulator receiver domain	IPR001789	Signal transduction response regulator, receiver domain	670	780	4.7E-27
CDD	cd17546	REC_hyHK_CKI1_RcsC-like	-	-	670	781	8.55386E-50
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	570	584	1.0E-12
Pfam	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	IPR003594	Histidine kinase/HSP90-like ATPase	530	644	5.1E-23
Pfam	PF07695	7TM diverse intracellular signalling	IPR011623	7TM-DISM receptor, extracellular domain, type 1	184	386	5.5E-56
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	605	623	1.0E-12
Coils	Coil	Coil	-	-	391	425	-
SMART	SM00448	REC_2	IPR001789	Signal transduction response regulator, receiver domain	668	781	5.5E-39
PANTHER	PTHR45339	HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J	-	-	365	649	3.2E-121
CDD	cd00082	HisKA	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	416	477	8.6091E-13
SUPERFAMILY	SSF55874	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	472	642	5.76E-37
CDD	cd16922	HATPase_EvgS-ArcB-TorS-like	-	-	535	643	5.8109E-49
SMART	SM00387	HKATPase_4	IPR003594	Histidine kinase/HSP90-like ATPase	530	645	1.2E-29
Pfam	PF00512	His Kinase A (phospho-acceptor) domain	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	419	482	2.2E-14

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.