Pseudomonas aeruginosa PAO1, PA3977 (hemL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0051188 obsolete cofactor biosynthetic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0015994 chlorophyll metabolic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Molecular Function GO:0003755 peptidyl-prolyl cis-trans isomerase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0033014 tetrapyrrole biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00713
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030170 pyridoxal phosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00202
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0042286 glutamate-1-semialdehyde 2,1-aminomutase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00713
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008483 transaminase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00202
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00860 Porphyrin and chlorophyll metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-5188 tetrapyrrole biosynthesis I (from glutamate) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc P381-PWY adenosylcobalamin biosynthesis II (late cobalt incorporation) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Porphyrin and chlorophyll metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR43713 GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE - - 2 424 0.0
Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase 3 426 105.701233
SUPERFAMILY SSF53383 PLP-dependent transferases IPR015424 Pyridoxal phosphate-dependent transferase 2 424 0.0
FunFam G3DSA:3.40.640.10:FF:000021 Glutamate-1-semialdehyde 2,1-aminomutase - - 69 317 4.8E-127
NCBIfam TIGR00713 JCVI: glutamate-1-semialdehyde 2,1-aminomutase IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase 4 424 0.0
Pfam PF00202 Aminotransferase class-III IPR005814 Aminotransferase class-III 32 394 3.7E-78
CDD cd00610 OAT_like IPR005814 Aminotransferase class-III 7 423 0.0
Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase, domain 1 IPR015422 Pyridoxal phosphate-dependent transferase, small domain 6 419 0.0
Gene3D G3DSA:3.40.640.10 - IPR015421 Pyridoxal phosphate-dependent transferase, major domain 69 317 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.