Pseudomonas aeruginosa PAO1, PA4043 (ispA)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0033850	Z-farnesyl diphosphate synthase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	15809342	Reviewed by curator
Biological Process	GO:0051188	obsolete cofactor biosynthetic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0008299	isoprenoid biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:cd00685	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae01130	Biosynthesis of antibiotics	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Terpenoid biosynthesis		ECO:0000037 not_recorded
KEGG	pae01110	Biosynthesis of secondary metabolites	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	PWY-5123	trans, trans-farnesyl diphosphate biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00900	Terpenoid backbone biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
SFLD	SFLDS00005	Isoprenoid Synthase Type I	-	-	5	293	0.0
Gene3D	G3DSA:1.10.600.10	Farnesyl Diphosphate Synthase	IPR008949	Isoprenoid synthase domain superfamily	1	295	3.3E-107
PANTHER	PTHR43281	FARNESYL DIPHOSPHATE SYNTHASE	-	-	4	294	7.6E-95
SFLD	SFLDG01017	Polyprenyl Transferase Like	-	-	5	293	0.0
CDD	cd00685	Trans_IPPS_HT	IPR000092	Polyprenyl synthetase	26	293	5.96663E-76
FunFam	G3DSA:1.10.600.10:FF:000001	Geranylgeranyl diphosphate synthase	-	-	1	295	1.1E-115
SUPERFAMILY	SSF48576	Terpenoid synthases	IPR008949	Isoprenoid synthase domain superfamily	5	287	1.41E-86
Pfam	PF00348	Polyprenyl synthetase	IPR000092	Polyprenyl synthetase	29	259	5.4E-58

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.