Pseudomonas aeruginosa PAO1, PA4197 (bfiS)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:1900233	positive regulation of single-species biofilm formation on inanimate substrate	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	19936057	Reviewed by curator
Molecular Function	GO:0000155	phosphorelay sensor kinase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	19936057	Reviewed by curator
Biological Process	GO:0007165	signal transduction	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00512	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0000155	phosphorelay sensor kinase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00512	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016772	transferase activity, transferring phosphorus-containing groups	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0016310	phosphorylation	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005515	protein binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF08447	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCAP		Two-component System		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	713	731	1.1E-9
SMART	SM00091	pas_2	IPR000014	PAS domain	268	334	2.8E-9
NCBIfam	TIGR00229	JCVI: PAS domain S-box protein	IPR000014	PAS domain	268	389	1.1E-21
SMART	SM00091	pas_2	IPR000014	PAS domain	158	220	66.0
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	684	698	1.1E-9
SUPERFAMILY	SSF55785	PYP-like sensor domain (PAS domain)	IPR035965	PAS domain superfamily	273	386	9.99E-27
Gene3D	G3DSA:3.30.565.10	-	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	599	755	3.3E-33
SMART	SM00387	HKATPase_4	IPR003594	Histidine kinase/HSP90-like ATPase	641	753	3.6E-24
SUPERFAMILY	SSF55874	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	590	751	7.07E-33
SUPERFAMILY	SSF47384	Homodimeric domain of signal transducing histidine kinase	IPR036097	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily	522	597	4.71E-7
Pfam	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	IPR003594	Histidine kinase/HSP90-like ATPase	642	751	7.3E-15
SMART	SM00086	pac_2	IPR001610	PAC motif	462	504	21.0
SMART	SM00086	pac_2	IPR001610	PAC motif	340	383	4.8E-7
FunFam	G3DSA:3.30.565.10:FF:000459	Globin-coupled histidine kinase	-	-	599	755	7.8E-92
Gene3D	G3DSA:1.10.287.130	-	-	-	531	597	5.4E-19
CDD	cd00130	PAS	IPR000014	PAS domain	277	380	7.30277E-16
Coils	Coil	Coil	-	-	499	519	-
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	702	712	1.1E-9
CDD	cd00082	HisKA	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	524	595	2.09598E-5
SUPERFAMILY	SSF55785	PYP-like sensor domain (PAS domain)	IPR035965	PAS domain superfamily	382	502	1.93E-10
SMART	SM00091	pas_2	IPR000014	PAS domain	391	457	2.6
SMART	SM00388	HisKA_10	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	526	599	5.6E-5
Pfam	PF00512	His Kinase A (phospho-acceptor) domain	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	527	597	3.1E-8
Gene3D	G3DSA:3.30.450.20	PAS domain	-	-	401	518	1.1E-9
PANTHER	PTHR43065	SENSOR HISTIDINE KINASE	-	-	317	755	8.9E-55
CDD	cd00130	PAS	IPR000014	PAS domain	402	501	8.3341E-4
Pfam	PF08447	PAS fold	IPR013655	PAS fold-3	291	376	2.4E-15
Gene3D	G3DSA:3.30.450.20	PAS domain	-	-	267	400	2.3E-30

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.