Pseudomonas aeruginosa PAO1, PA4398

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:1900232 negative regulation of single-species biofilm formation on inanimate substrate
ISO
Inferred from Sequence Orthology
Term mapped from: Pseudocap:PA14_57170
 ECO:0000201
sequence orthology evidence		 19592586 Reviewed by curator
Biological Process GO:2000147 positive regulation of cell motility
ISO
Inferred from Sequence Orthology
Term mapped from: Pseudocap:PA14_57170
 ECO:0000201
sequence orthology evidence		 19592586 Reviewed by curator
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00512
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00672
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00512
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Two-component System ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 554 666 7.8E-21
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 506 665 1.7E-35
CDD cd00130 PAS IPR000014 PAS domain 296 394 3.27459E-4
NCBIfam TIGR00229 JCVI: PAS domain S-box protein IPR000014 PAS domain 288 402 1.5E-5
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 414 498 3.96305E-6
SMART SM00091 pas_2 IPR000014 PAS domain 287 352 3.8E-5
MobiDBLite mobidb-lite consensus disorder prediction - - 670 698 -
SMART SM00304 HAMP_11 IPR003660 HAMP domain 185 238 1.4E-8
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 651 664 1.9E-14
Gene3D G3DSA:3.30.450.20 PAS domain - - 266 399 4.7E-14
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 408 502 2.55E-7
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 414 499 9.4E-10
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 550 667 2.5E-26
PANTHER PTHR43065 SENSOR HISTIDINE KINASE - - 205 670 3.9E-64
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 613 623 1.9E-14
Gene3D G3DSA:1.10.287.130 - - - 404 500 3.0E-22
SUPERFAMILY SSF158472 HAMP domain-like - - 185 234 3.27E-7
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 626 644 1.9E-14
Coils Coil Coil - - 230 271 -
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 412 502 2.6E-5
CDD cd06225 HAMP - - 188 233 8.31356E-8
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 595 609 1.9E-14
Pfam PF08448 PAS fold IPR013656 PAS fold-4 294 397 7.3E-9
Pfam PF00672 HAMP domain IPR003660 HAMP domain 183 234 1.8E-8
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 505 675 4.0E-38
Gene3D G3DSA:6.10.340.10 - - - 155 243 1.8E-13
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 275 395 4.54E-12

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.