Pseudomonas aeruginosa PAO1, PA4489 (magD)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0004866 | endopeptidase inhibitor activity |
Inferred from Sequence Model
Term mapped from: InterPro:SM01360
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
|
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Gene3D | G3DSA:2.20.130.20 | - | - | - | 743 | 909 | 3.0E-7 |
| Pfam | PF00207 | Alpha-2-macroglobulin family | IPR001599 | Alpha-2-macroglobulin | 857 | 944 | 8.9E-24 |
| PANTHER | PTHR11412 | MACROGLOBULIN / COMPLEMENT | - | - | 702 | 1124 | 1.6E-39 |
| Pfam | PF01835 | MG2 domain | IPR002890 | Macroglobulin domain | 333 | 428 | 1.3E-19 |
| SMART | SM01360 | A2M_2 | IPR001599 | Alpha-2-macroglobulin | 857 | 947 | 2.1E-26 |
| SUPERFAMILY | SSF48239 | Terpenoid cyclases/Protein prenyltransferases | IPR008930 | Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid | 1043 | 1147 | 3.88E-14 |
| SMART | SM01419 | Thiol_ester_cl_2 | IPR047565 | Alpha-macroglobulin-like, thiol-ester bond-forming region | 1045 | 1074 | 5.9E-6 |
| SMART | SM01359 | A2M_N_2_2 | IPR011625 | Alpha-2-macroglobulin, bait region domain | 646 | 792 | 1.1E-26 |
| Gene3D | G3DSA:1.50.10.20 | - | - | - | 1043 | 1336 | 2.4E-12 |
| Gene3D | G3DSA:2.60.40.1930 | - | - | - | 332 | 432 | 3.0E-15 |
| Pfam | PF07703 | Alpha-2-macroglobulin bait region domain | IPR011625 | Alpha-2-macroglobulin, bait region domain | 647 | 792 | 2.0E-12 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.