Pseudomonas aeruginosa PAO1, PA4519 (speC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0033387 putrescine biosynthetic process from ornithine
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 12634339 Reviewed by curator
Molecular Function GO:0004586 ornithine decarboxylase activity
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 12634339 Reviewed by curator
Biological Process GO:0006596 polyamine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR11482
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02784
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Arginine and proline metabolism ECO:0000037
not_recorded
PseudoCyc ORNDEG-PWY superpathway of ornithine degradation 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00330 Arginine and proline metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc POLYAMSYN-PWY superpathway of polyamine biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc ORNSPNANA-PWY ornithine spermine biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-46 putrescine biosynthesis III 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00480 Glutathione metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.20.20.10 Alanine racemase IPR029066 PLP-binding barrel 33 273 1.5E-89
PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature IPR000183 Ornithine/DAP/Arg decarboxylase 261 280 3.8E-18
PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature IPR000183 Ornithine/DAP/Arg decarboxylase 54 72 3.8E-18
PRINTS PR01182 Ornithine decarboxylase signature IPR002433 Ornithine decarboxylase 96 120 1.1E-18
Gene3D G3DSA:2.40.37.10 Lyase, Ornithine Decarboxylase; Chain A, domain 1 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal 21 380 1.5E-89
PRINTS PR01182 Ornithine decarboxylase signature IPR002433 Ornithine decarboxylase 329 339 1.1E-18
SUPERFAMILY SSF50621 Alanine racemase C-terminal domain-like IPR009006 Alanine racemase/group IV decarboxylase, C-terminal 245 386 1.51E-30
Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal 272 365 3.1E-14
PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature IPR000183 Ornithine/DAP/Arg decarboxylase 177 190 3.8E-18
PRINTS PR01182 Ornithine decarboxylase signature IPR002433 Ornithine decarboxylase 52 79 1.1E-18
PRINTS PR01182 Ornithine decarboxylase signature IPR002433 Ornithine decarboxylase 126 148 1.1E-18
PRINTS PR01182 Ornithine decarboxylase signature IPR002433 Ornithine decarboxylase 26 50 1.1E-18
Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal 35 271 5.4E-55
PANTHER PTHR11482 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE IPR002433 Ornithine decarboxylase 23 386 1.1E-80
FunFam G3DSA:2.40.37.10:FF:000004 Ornithine decarboxylase - - 265 380 2.4E-59
FunFam G3DSA:3.20.20.10:FF:000008 Ornithine decarboxylase - - 34 269 3.0E-94
PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature IPR000183 Ornithine/DAP/Arg decarboxylase 74 86 3.8E-18
CDD cd00622 PLPDE_III_ODC - - 25 387 0.0
SUPERFAMILY SSF51419 PLP-binding barrel IPR029066 PLP-binding barrel 25 273 4.86E-66

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.