Pseudomonas aeruginosa PAO1, PA4528 (pilD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006480 N-terminal protein amino acid methylation
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 23255525 Reviewed by curator
Cellular Component GO:0005886 plasma membrane
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 9466269 Reviewed by curator
Molecular Function GO:0004190 aspartic-type endopeptidase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 23255525 Reviewed by curator
Molecular Function GO:0008170 N-methyltransferase activity
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 8096341 Reviewed by curator
Biological Process GO:0006465 signal peptide processing
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 8096341 Reviewed by curator
Biological Process GO:0043683 type IV pilus biogenesis
IMP
Inferred from Mutant Phenotype 		ECO:0000315
mutant phenotype evidence used in manual assertion		 1671384 Reviewed by curator
Cellular Component GO:0015627 type II protein secretion system complex
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 1588814 Reviewed by curator
Biological Process GO:0009297 pilus assembly
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 9668097 Reviewed by curator
Molecular Function GO:0004190 aspartic-type endopeptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01478
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01478
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Secreted Factors (toxins, enzymes, alginate) Other PAO1 genes in this class
Protein secretion/export apparatus Other PAO1 genes in this class
Motility & Attachment Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Pilin biosynthesis ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF06750 Bacterial Peptidase A24 N-terminal domain IPR010627 Peptidase A24A, N-terminal 20 126 7.0E-34
PANTHER PTHR30487 TYPE 4 PREPILIN-LIKE PROTEINS LEADER PEPTIDE-PROCESSING ENZYME - - 13 286 8.4E-89
PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature IPR014032 Peptidase A24A, prepilin type IV, bacterial 145 162 1.5E-26
PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature IPR014032 Peptidase A24A, prepilin type IV, bacterial 213 224 1.5E-26
Pfam PF01478 Type IV leader peptidase family IPR000045 Prepilin type IV endopeptidase, peptidase domain 137 245 8.9E-25
FunFam G3DSA:1.20.120.1220:FF:000001 Type 4 prepilin-like proteins leader peptide-processing enzyme - - 128 286 9.7E-76
PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature IPR014032 Peptidase A24A, prepilin type IV, bacterial 202 212 1.5E-26
PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature IPR014032 Peptidase A24A, prepilin type IV, bacterial 225 240 1.5E-26
Gene3D G3DSA:1.20.120.1220 - - - 111 286 2.8E-13

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.