Pseudomonas aeruginosa PAO1, PA4640 (mqoB)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0008924	malate dehydrogenase (quinone) activity	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	12480887	Reviewed by curator
Molecular Function	GO:0008924	malate dehydrogenase (quinone) activity	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	12480887	Reviewed by curator
Biological Process	GO:0006069	ethanol oxidation	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	12480887	Reviewed by curator
Biological Process	GO:0006069	ethanol oxidation	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	12480887	Reviewed by curator
Biological Process	GO:0006099	tricarboxylic acid cycle	ISM Inferred from Sequence Model Term mapped from: InterPro:PF06039	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0008924	malate dehydrogenase (quinone) activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF06039	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Energy metabolism Other PAO1 genes in this class Central intermediary metabolism Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCyc	TCA-GLYOX-BYPASS	superpathway of glyoxylate bypass and TCA	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae01200	Carbon metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	TCA	TCA cycle I (prokaryotic)	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCAP		Citrate cycle (TCA cycle)		ECO:0000037 not_recorded
PseudoCyc	GLYCOLYSIS-TCA-GLYOX-BYPASS	superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae00620	Pyruvate metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01120	Microbial metabolism in diverse environments	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01110	Biosynthesis of secondary metabolites	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Pyruvate metabolism		ECO:0000037 not_recorded
KEGG	pae01130	Biosynthesis of antibiotics	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00020	Citrate cycle (TCA cycle)	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PANTHER	PTHR43104	L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL	-	-	3	442	2.0E-26
Gene3D	G3DSA:3.30.9.10	-	-	-	114	311	5.2E-11
SUPERFAMILY	SSF51905	FAD/NAD(P)-binding domain	IPR036188	FAD/NAD(P)-binding domain superfamily	8	275	1.37E-25
Pfam	PF06039	Malate:quinone oxidoreductase (Mqo)	IPR006231	Malate:quinone-oxidoreductase	8	494	0.0
Hamap	MF_00212	Probable malate:quinone oxidoreductase [mqo].	IPR006231	Malate:quinone-oxidoreductase	5	494	54.16206
NCBIfam	TIGR01320	JCVI: malate dehydrogenase (quinone)	IPR006231	Malate:quinone-oxidoreductase	9	492	0.0
Gene3D	G3DSA:3.50.50.60	-	IPR036188	FAD/NAD(P)-binding domain superfamily	10	264	5.2E-11

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.