Pseudomonas aeruginosa PAO1, PA4695 (ilvH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003984 acetolactate synthase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 9581571 Reviewed by curator
Cellular Component GO:0005948 acetolactate synthase complex
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 9581571 Reviewed by curator
Biological Process GO:0009082 branched-chain amino acid biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 9581571 Reviewed by curator
Biological Process GO:0009082 branched-chain amino acid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR30239
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:1990610 acetolactate synthase regulator activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR30239
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class
Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCyc BRANCHED-CHAIN-AA-SYN-PWY superpathway of branched amino acid biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00660 C5-Branched dibasic acid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Pantothenate and CoA biosynthesis ECO:0000037
not_recorded
KEGG pae01210 2-Oxocarboxylic acid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc ILEUSYN-PWY L-isoleucine biosynthesis I (from threonine) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00650 Butanoate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Valine, leucine and isoleucine biosynthesis ECO:0000037
not_recorded
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00290 Valine, leucine and isoleucine biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00770 Pantothenate and CoA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Butanoate metabolism ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP C5-Branched dibasic acid metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF10369 Small subunit of acetolactate synthase IPR019455 Acetolactate synthase, small subunit, C-terminal 84 157 7.9E-27
Gene3D G3DSA:3.30.70.260 - - - 1 79 1.8E-35
Gene3D G3DSA:3.30.70.1150 - IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal 83 163 6.7E-31
NCBIfam TIGR00119 JCVI: acetolactate synthase small subunit IPR004789 Acetolactate synthase, small subunit 1 158 5.5E-63
SUPERFAMILY SSF55021 ACT-like IPR045865 ACT-like domain 1 75 2.45E-21
FunFam G3DSA:3.30.70.1150:FF:000001 Acetolactate synthase small subunit - - 83 159 1.3E-27
SUPERFAMILY SSF55021 ACT-like IPR045865 ACT-like domain 79 162 2.29E-26
CDD cd04878 ACT_AHAS IPR039557 AHAS, ACT domain 3 72 6.61597E-30
Pfam PF13710 ACT domain - - 12 72 8.7E-15
FunFam G3DSA:3.30.70.260:FF:000001 Acetolactate synthase, small subunit - - 1 79 9.5E-36
PANTHER PTHR30239 ACETOLACTATE SYNTHASE SMALL SUBUNIT IPR004789 Acetolactate synthase, small subunit 2 158 2.7E-51

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.