Pseudomonas aeruginosa PAO1, PA4762 (grpE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000774 adenyl-nucleotide exchange factor activity

Biological Process GO:0006508 proteolysis
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 3149251 Reviewed by curator
Biological Process GO:0034605 cellular response to heat
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 2424889 Reviewed by curator
Biological Process GO:0006457 protein folding
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 8898387 Reviewed by curator
Molecular Function GO:0042803 protein homodimerization activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01151
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051087 chaperone binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01151
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006457 protein folding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01151
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000774 adenyl-nucleotide exchange factor activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01151
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Chaperones & heat shock proteins Other PAO1 genes in this class
DNA replication, recombination, modification and repair Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00773 GrpE protein signature IPR000740 GrpE nucleotide exchange factor 125 140 2.8E-25
Coils Coil Coil - - 20 58 -
FunFam G3DSA:3.90.20.20:FF:000014 Protein GrpE - - 6 116 2.3E-56
MobiDBLite mobidb-lite consensus disorder prediction - - 1 18 -
Gene3D G3DSA:2.30.22.10 Head domain of nucleotide exchange factor GrpE IPR009012 GrpE nucleotide exchange factor, head 118 173 4.8E-21
Gene3D G3DSA:3.90.20.20 - IPR013805 GrpE nucleotide exchange factor, coiled-coil 2 114 6.4E-26
SUPERFAMILY SSF58014 Coiled-coil domain of nucleotide exchange factor GrpE IPR013805 GrpE nucleotide exchange factor, coiled-coil 20 115 1.16E-26
MobiDBLite mobidb-lite consensus disorder prediction - - 1 20 -
FunFam G3DSA:2.30.22.10:FF:000001 Protein GrpE - - 117 172 3.1E-23
Pfam PF01025 GrpE IPR000740 GrpE nucleotide exchange factor 13 173 8.0E-52
PRINTS PR00773 GrpE protein signature IPR000740 GrpE nucleotide exchange factor 70 85 2.8E-25
PANTHER PTHR21237 GRPE PROTEIN IPR000740 GrpE nucleotide exchange factor 22 175 1.3E-41
PRINTS PR00773 GrpE protein signature IPR000740 GrpE nucleotide exchange factor 152 171 2.8E-25
CDD cd00446 GrpE IPR000740 GrpE nucleotide exchange factor 35 171 4.68856E-60
PRINTS PR00773 GrpE protein signature IPR000740 GrpE nucleotide exchange factor 42 58 2.8E-25
Hamap MF_01151 Protein GrpE [grpE]. IPR000740 GrpE nucleotide exchange factor 3 173 20.577837
SUPERFAMILY SSF51064 Head domain of nucleotide exchange factor GrpE IPR009012 GrpE nucleotide exchange factor, head 118 174 4.97E-19

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.