Pseudomonas aeruginosa PAO1, PA4878 (brlR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 22730129 Reviewed by curator
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 23935054 Reviewed by curator
Molecular Function GO:0003700 DNA-binding transcription factor activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR30204
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00422
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00422
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF14526 Integron-associated effector binding protein IPR029441 Integron-associated effector binding protein 123 269 1.2E-36
Gene3D G3DSA:3.20.80.10 Regulatory factor, effector binding domain IPR011256 Regulatory factor, effector binding domain superfamily 124 270 7.2E-39
SMART SM00422 merrmega3 IPR000551 MerR-type HTH domain 2 72 4.8E-20
FunFam G3DSA:3.20.80.10:FF:000016 Probable transcriptional regulator - - 124 270 1.8E-103
SMART SM00871 AraC_E_bind_2 IPR010499 Bacterial transcription activator, effector binding 120 270 1.4E-33
SUPERFAMILY SSF55136 Probable bacterial effector-binding domain IPR011256 Regulatory factor, effector binding domain superfamily 120 269 1.05E-32
CDD cd01107 HTH_BmrR - - 2 112 1.83943E-42
PANTHER PTHR30204 REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR IPR047057 MerR transcriptional regulator 1 112 2.4E-21
Pfam PF13411 MerR HTH family regulatory protein IPR000551 MerR-type HTH domain 3 68 1.0E-15
SUPERFAMILY SSF46955 Putative DNA-binding domain IPR009061 Putative DNA-binding domain superfamily 2 108 1.31E-25
Gene3D G3DSA:1.10.1660.10 - - - 1 123 3.4E-26
FunFam G3DSA:1.10.1660.10:FF:000016 MerR family transcriptional regulator - - 1 123 6.5E-61

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.