Pseudomonas aeruginosa PAO1, PA5134 (ctpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0030313 cell envelope
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 21204920 Reviewed by curator
Biological Process GO:0030254 protein secretion by the type III secretion system
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 24082078 Reviewed by curator
Biological Process GO:0009405 pathogenesis
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 24082078 Reviewed by curator
Biological Process GO:0007165 signal transduction
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 24928312 Reviewed by curator
Cellular Component GO:0005886 plasma membrane
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 21204920 Reviewed by curator
Biological Process GO:0042546 cell wall biogenesis
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 24928312 Reviewed by curator
Molecular Function GO:0004252 serine-type endopeptidase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:P23865
 ECO:0000250
sequence similarity evidence used in manual assertion		 24928312 Reviewed by curator
Cellular Component GO:0042597 periplasmic space
IDA
Inferred from Direct Assay 		ECO:0000004
cell fractionation evidence		 21204920 Reviewed by curator
Cellular Component GO:0042597 periplasmic space
IDA
Inferred from Direct Assay 		ECO:0000004
cell fractionation evidence		 24082078 Reviewed by curator
Biological Process GO:0043163 cell envelope organization
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 24082078 Reviewed by curator
Molecular Function GO:0005515 protein binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:2.30.42.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008236 serine-type peptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00225
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006508 proteolysis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00225
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Translation, post-translational modification, degradation Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR00225 JCVI: C-terminal processing peptidase IPR004447 C-terminal-processing peptidase S41A 59 376 2.9E-105
SUPERFAMILY SSF52096 ClpP/crotonase IPR029045 ClpP/crotonase-like domain superfamily 42 370 1.06E-82
Pfam PF02163 Peptidase family M50 IPR008915 Peptidase M50 121 224 4.9E-8
Pfam PF17820 PDZ domain IPR041489 PDZ domain 6 120 174 1.4E-16
Gene3D G3DSA:3.30.750.44 - - - 53 344 6.1E-94
FunFam G3DSA:3.90.226.10:FF:000029 Peptidase, S41 family - - 192 366 3.3E-60
Pfam PF03572 Peptidase family S41 IPR005151 Tail specific protease 203 368 1.9E-57
FunFam G3DSA:2.30.42.10:FF:000063 Peptidase, S41 family - - 105 191 7.3E-29
MobiDBLite mobidb-lite consensus disorder prediction - - 389 419 -
SMART SM00228 pdz_new IPR001478 PDZ domain 105 176 1.6E-17
CDD cd07560 Peptidase_S41_CPP IPR004447 C-terminal-processing peptidase S41A 44 368 9.27658E-97
FunFam G3DSA:3.30.750.44:FF:000001 S41 family peptidase - - 54 113 6.7E-17
SUPERFAMILY SSF50156 PDZ domain-like IPR036034 PDZ superfamily 97 178 8.87E-20
SMART SM00245 tsp_4 IPR005151 Tail specific protease 177 369 1.8E-75
Gene3D G3DSA:3.90.226.10 - - - 192 366 6.1E-94
CDD cd00988 PDZ_CTP_protease - - 104 188 2.60482E-28
Gene3D G3DSA:2.30.42.10 - IPR036034 PDZ superfamily 105 191 6.1E-94
PANTHER PTHR32060 TAIL-SPECIFIC PROTEASE - - 44 373 1.9E-88

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.