Pseudomonas aeruginosa PAO1, PA5162 (rmlD)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Cellular Component	GO:0009276	Gram-negative-bacterium-type cell wall	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0009244	lipopolysaccharide core region biosynthetic process	ISS Inferred from Sequence or Structural Similarity Term mapped from: UniProtKB:P37760	ECO:0000250 sequence similarity evidence used in manual assertion	11065359	Reviewed by curator
Biological Process	GO:0009243	O antigen biosynthetic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	9023210	Reviewed by curator
Molecular Function	GO:0008831	dTDP-4-dehydrorhamnose reductase activity	ISS Inferred from Sequence or Structural Similarity Term mapped from: UniProtKB:P37760	ECO:0000250 sequence similarity evidence used in manual assertion	11065359	Reviewed by curator
Molecular Function	GO:0008831	dTDP-4-dehydrorhamnose reductase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	10455186	Reviewed by curator
Biological Process	GO:0019305	dTDP-rhamnose biosynthetic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	10455186	Reviewed by curator
Biological Process	GO:0019305	dTDP-rhamnose biosynthetic process	ISS Inferred from Sequence or Structural Similarity Term mapped from: UniProtKB:P37760	ECO:0000250 sequence similarity evidence used in manual assertion	11065359	Reviewed by curator

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae00521	Streptomycin biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Lipopolysaccharide biosynthesis		ECO:0000037 not_recorded
PseudoCAP		Nucleotide sugars metabolism		ECO:0000037 not_recorded
PseudoCyc	DTDPRHAMSYN-PWY	dTDP-L-rhamnose biosynthesis I	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCyc	OANTIGEN-PWY	O-antigen building blocks biosynthesis (E. coli)	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00523	Polyketide sugar unit biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01130	Biosynthesis of antibiotics	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PANTHER	PTHR10491	DTDP-4-DEHYDRORHAMNOSE REDUCTASE	IPR005913	dTDP-4-dehydrorhamnose reductase family	2	297	1.0E-66
NCBIfam	TIGR01214	JCVI: dTDP-4-dehydrorhamnose reductase	IPR005913	dTDP-4-dehydrorhamnose reductase family	3	295	4.3E-115
Pfam	PF04321	RmlD substrate binding domain	IPR029903	RmlD-like substrate binding domain	3	296	8.2E-112
Gene3D	G3DSA:3.40.50.720	-	-	-	4	283	2.0E-106
Gene3D	G3DSA:3.90.25.10	-	-	-	159	286	2.0E-106
SUPERFAMILY	SSF51735	NAD(P)-binding Rossmann-fold domains	IPR036291	NAD(P)-binding domain superfamily	1	296	1.46E-95
CDD	cd05254	dTDP_HR_like_SDR_e	-	-	3	286	4.01731E-97

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.