Pseudomonas aeruginosa PAO1, PA5165 (dctB)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0032892	positive regulation of organic acid transport	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	21725012	Reviewed by curator
Molecular Function	GO:0000155	phosphorelay sensor kinase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	21725012	Reviewed by curator
Biological Process	GO:0007165	signal transduction	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00512	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016772	transferase activity, transferring phosphorus-containing groups	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0000155	phosphorelay sensor kinase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00512	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0016310	phosphorylation	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transport of small molecules Other PAO1 genes in this class Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae02020	Two-component system	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Two-component System		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF02743	Cache domain	IPR033479	Double Cache domain 1	48	276	2.2E-15
FunFam	G3DSA:3.30.450.20:FF:000127	C4-dicarboxylate transport sensor protein	-	-	113	190	1.2E-37
CDD	cd00082	HisKA	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	376	442	3.35391E-9
SUPERFAMILY	SSF103190	Sensory domain-like	IPR029151	Periplasmic sensor-like domain superfamily	68	203	2.35E-19
Gene3D	G3DSA:3.30.565.10	-	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	447	597	3.2E-32
PIRSF	PIRSF036431	HK_DctB	IPR017055	Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator)	4	605	0.0
CDD	cd22249	UDM1_RNF168_RNF169-like	-	-	324	371	0.00307773
Gene3D	G3DSA:6.10.250.3020	-	-	-	49	110	4.9E-5
Gene3D	G3DSA:3.30.450.20	PAS domain	-	-	191	282	4.0E-20
Pfam	PF00512	His Kinase A (phospho-acceptor) domain	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	379	442	2.8E-8
Pfam	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	IPR003594	Histidine kinase/HSP90-like ATPase	490	595	3.5E-18
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	546	556	1.2E-8
SMART	SM00387	HKATPase_4	IPR003594	Histidine kinase/HSP90-like ATPase	488	599	1.4E-24
FunFam	G3DSA:1.10.287.130:FF:000049	C4-dicarboxylate transport sensor protein DctB	-	-	354	441	2.6E-38
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	528	542	1.2E-8
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	559	577	1.2E-8
Gene3D	G3DSA:3.30.450.20	PAS domain	-	-	113	190	7.1E-29
PANTHER	PTHR43065	SENSOR HISTIDINE KINASE	-	-	192	595	1.2E-51
Gene3D	G3DSA:1.10.287.130	-	-	-	354	441	3.0E-19
SUPERFAMILY	SSF55874	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	437	595	1.28E-33
Coils	Coil	Coil	-	-	328	376	-
SUPERFAMILY	SSF47384	Homodimeric domain of signal transducing histidine kinase	IPR036097	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily	366	442	1.9E-11
SMART	SM00388	HisKA_10	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	378	446	4.9E-7

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.