Pseudomonas aeruginosa PAO1, PA5320 (coaC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0015937 coenzyme A biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:G0HKG0
 ECO:0000250
sequence similarity evidence used in manual assertion		 11278255 Reviewed by curator
Molecular Function GO:0004632 phosphopantothenate--cysteine ligase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:P0ABQ0
 ECO:0000250
sequence similarity evidence used in manual assertion		 11278255 Reviewed by curator
Molecular Function GO:0004633 phosphopantothenoylcysteine decarboxylase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:P0ABQ0
 ECO:0000250
sequence similarity evidence used in manual assertion		 11278255 Reviewed by curator
Molecular Function GO:0010181 FMN binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00521
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0015941 pantothenate catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00521
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004632 phosphopantothenate--cysteine ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00521
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004633 phosphopantothenoylcysteine decarboxylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00521
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.1950
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0015937 coenzyme A biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00521
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other PAO1 genes in this class
Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00770 Pantothenate and CoA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF02441 Flavoprotein IPR003382 Flavoprotein 7 179 1.7E-41
FunFam G3DSA:3.40.50.10300:FF:000001 Coenzyme A biosynthesis bifunctional protein CoaBC - - 185 402 1.8E-97
Pfam PF04127 DNA / pantothenate metabolism flavoprotein IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal 186 370 2.5E-71
Gene3D G3DSA:3.40.50.10300 - IPR035929 CoaB-like superfamily 186 402 1.7E-74
NCBIfam TIGR00521 JCVI: bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC 6 395 0.0
Hamap MF_02225 Coenzyme A biosynthesis bifunctional protein CoaBC [coaBC]. IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC 7 398 59.598213
FunFam G3DSA:3.40.50.1950:FF:000002 Coenzyme A biosynthesis bifunctional protein CoaBC - - 1 185 1.2E-101
SUPERFAMILY SSF52507 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD IPR036551 Flavin prenyltransferase-like 1 179 2.35E-59
Gene3D G3DSA:3.40.50.1950 - IPR036551 Flavin prenyltransferase-like 1 185 2.6E-56
PANTHER PTHR14359 HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY - - 6 248 1.0E-49
SUPERFAMILY SSF102645 CoaB-like IPR035929 CoaB-like superfamily 184 400 5.89E-76

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.