Pseudomonas aeruginosa PAO1, PA5361 (phoR)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0000155	phosphorelay sensor kinase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	11703664	Reviewed by curator
Biological Process	GO:0000160	phosphorelay signal transduction system	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:1900231	regulation of single-species biofilm formation on inanimate substrate	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	11703664	Reviewed by curator
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF11808	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Cellular Component	GO:0016020	membrane	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR02966	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016772	transferase activity, transferring phosphorus-containing groups	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0016310	phosphorylation	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0007165	signal transduction	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF47384	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006355	regulation of transcription, DNA-templated	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00989	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0004673	protein histidine kinase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR02966	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0000160	phosphorelay signal transduction system	ISM Inferred from Sequence Model Term mapped from: InterPro:PF11808	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0000155	phosphorelay sensor kinase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF47384	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae02020	Two-component system	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Two-component System		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PANTHER	PTHR45453	PHOSPHATE REGULON SENSOR PROTEIN PHOR	-	-	10	436	0.0
Gene3D	G3DSA:3.30.450.20	PAS domain	-	-	108	202	4.8E-8
SUPERFAMILY	SSF55785	PYP-like sensor domain (PAS domain)	IPR035965	PAS domain superfamily	113	208	1.12E-7
Gene3D	G3DSA:1.10.287.130	-	-	-	203	275	1.6E-21
Pfam	PF00989	PAS fold	IPR013767	PAS fold	102	156	1.7E-5
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	393	411	1.2E-11
SMART	SM00091	pas_2	IPR000014	PAS domain	102	170	6.6E-5
CDD	cd16952	HATPase_EcPhoR-like	-	-	326	433	2.49875E-69
SUPERFAMILY	SSF47384	Homodimeric domain of signal transducing histidine kinase	IPR036097	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily	195	276	7.65E-22
FunFam	G3DSA:3.30.565.10:FF:000032	Phosphate regulon sensor histidine kinase PhoR	-	-	282	436	2.0E-62
Pfam	PF11808	Phosphate regulon sensor protein PhoR	IPR021766	Phosphate regulon sensor protein PhoR	9	94	4.7E-28
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	358	372	1.2E-11
Pfam	PF00512	His Kinase A (phospho-acceptor) domain	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	209	275	1.0E-18
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	417	430	1.2E-11
FunFam	G3DSA:3.30.450.20:FF:000076	Phosphate regulon sensor histidine kinase PhoR	-	-	86	204	1.4E-71
CDD	cd00082	HisKA	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	207	262	1.12735E-13
SUPERFAMILY	SSF55874	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	265	429	1.57E-40
SMART	SM00387	HKATPase_4	IPR003594	Histidine kinase/HSP90-like ATPase	321	433	2.4E-33
SMART	SM00388	HisKA_10	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	209	276	4.4E-21
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	376	386	1.2E-11
Gene3D	G3DSA:3.30.565.10	-	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	279	430	2.1E-36
CDD	cd00130	PAS	IPR000014	PAS domain	111	219	2.43328E-5
Pfam	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	IPR003594	Histidine kinase/HSP90-like ATPase	322	430	1.1E-24
Coils	Coil	Coil	-	-	250	270	-
FunFam	G3DSA:1.10.287.130:FF:000001	Two-component sensor histidine kinase	-	-	205	277	2.2E-25
NCBIfam	TIGR02966	JCVI: phosphate regulon sensor histidine kinase PhoR	IPR014310	Signal transduction histidine kinase, phosphate regulon sensor PhoR	98	429	0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.