Pseudomonas aeruginosa PAO1, PA5376 (cbcV)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0033266	ATPase-coupled choline transmembrane transporter activity	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Biological Process	GO:0031457	glycine betaine catabolic process	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Biological Process	GO:0015871	choline transport	IMP Inferred from Mutant Phenotype	ECO:0000015 mutant phenotype evidence	19919675	Reviewed by curator
Biological Process	GO:0042426	choline catabolic process	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Molecular Function	GO:0015226	carnitine transmembrane transporter activity	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Biological Process	GO:0015838	amino-acid betaine transport	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Biological Process	GO:1902603	carnitine transmembrane transport	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	21478341	Reviewed by curator
Biological Process	GO:0031460	glycine betaine transport	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	21478341	Reviewed by curator
Biological Process	GO:0042426	choline catabolic process	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	21478341	Reviewed by curator
Cellular Component	GO:0043190	ATP-binding cassette (ABC) transporter complex	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Biological Process	GO:0031460	glycine betaine transport	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Molecular Function	GO:0005275	amine transmembrane transporter activity	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Molecular Function	GO:0015418	ATPase-coupled quaternary ammonium compound transmembrane transporting activity	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Molecular Function	GO:0015419	ATPase-coupled sulfate transmembrane transporter activity	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	23763788	Reviewed by curator
Molecular Function	GO:0031459	ATPase-coupled glycine betaine transporter activity	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	19919675	Reviewed by curator
Molecular Function	GO:1901682	sulfur compound transmembrane transporter activity	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	23763788	Reviewed by curator
Molecular Function	GO:0015220	choline transmembrane transporter activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR03415	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005524	ATP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00005	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0015871	choline transport	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR03415	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016887	ATPase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:SM00382	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Cellular Component	GO:0055052	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR03415	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transport of small molecules Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae02010	ABC transporters	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Gene3D	G3DSA:3.40.50.300	-	IPR027417	P-loop containing nucleoside triphosphate hydrolase	31	294	1.0E-69
NCBIfam	TIGR03415	JCVI: choline ABC transporter ATP-binding protein	IPR022473	ABC transporter, Choline, ATP-binding subunit	4	389	0.0
SMART	SM00382	AAA_5	IPR003593	AAA+ ATPase domain	52	253	3.5E-15
PANTHER	PTHR43869	GLYCINE BETAINE/PROLINE BETAINE TRANSPORT SYSTEM ATP-BINDING PROTEIN PROV	-	-	2	390	0.0
SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	IPR027417	P-loop containing nucleoside triphosphate hydrolase	34	274	8.69E-70
Pfam	PF00005	ABC transporter	IPR003439	ABC transporter-like, ATP-binding domain	46	195	9.6E-28
FunFam	G3DSA:3.40.50.300:FF:000201	Glycine betaine/L-proline ABC transporter ATP-binding protein	-	-	31	288	3.7E-116

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.