Pseudomonas aeruginosa PAO1, PA5377 (cbcW)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0031460 glycine betaine transport
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
19919675 Reviewed by curator
Cellular Component GO:1902495 transmembrane transporter complex
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
19919675 Reviewed by curator
Biological Process GO:0031460 glycine betaine transport
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
21478341 Reviewed by curator
Molecular Function GO:0015226 carnitine transmembrane transporter activity
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
19919675 Reviewed by curator
Cellular Component GO:0043190 ATP-binding cassette (ABC) transporter complex
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
19919675 Reviewed by curator
Biological Process GO:1902603 carnitine transmembrane transport
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
21478341 Reviewed by curator
Molecular Function GO:0005275 amine transmembrane transporter activity
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
19919675 Reviewed by curator
Molecular Function GO:1901682 sulfur compound transmembrane transporter activity
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
23763788 Reviewed by curator
Biological Process GO:0015871 choline transport
IMP
Inferred from Mutant Phenotype
ECO:0000015
mutant phenotype evidence
19919675 Reviewed by curator
Biological Process GO:0042426 choline catabolic process
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
21478341 Reviewed by curator
Biological Process GO:0031457 glycine betaine catabolic process
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
19919675 Reviewed by curator
Biological Process GO:0015838 amino-acid betaine transport
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
19919675 Reviewed by curator
Biological Process GO:0042426 choline catabolic process
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
19919675 Reviewed by curator
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd06261
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055085 transmembrane transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd06261
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Membrane proteins Other PAO1 genes in this class
Transport of small molecules Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02010 ABC transporters 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR03416 JCVI: choline ABC transporter permease subunit IPR017784 ABC transporter, choline, permease protein 5 271 1.1E-125
FunFam G3DSA:1.10.3720.10:FF:000001 Glycine betaine ABC transporter, permease - - 85 277 6.4E-66
SUPERFAMILY SSF161098 MetI-like IPR035906 MetI-like superfamily 87 271 5.89E-39
CDD cd06261 TM_PBP2 IPR000515 ABC transporter type 1, transmembrane domain MetI-like 95 257 1.54646E-15
PANTHER PTHR47737 GLYCINE BETAINE/PROLINE BETAINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW - - 1 275 6.0E-100
Gene3D G3DSA:1.10.3720.10 - IPR035906 MetI-like superfamily 86 273 8.7E-34
Pfam PF00528 Binding-protein-dependent transport system inner membrane component IPR000515 ABC transporter type 1, transmembrane domain MetI-like 110 267 1.1E-27

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.