Pseudomonas aeruginosa PAO1, PA5483 (algB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000976 transcription regulatory region sequence-specific DNA binding
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 17981963 Reviewed by curator
Biological Process GO:0045862 positive regulation of proteolysis
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 23024348 Reviewed by curator
Biological Process GO:2000147 positive regulation of cell motility
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 23024348 Reviewed by curator
Biological Process GO:0042121 alginic acid biosynthetic process
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 1738315 Reviewed by curator
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 1738315 Reviewed by curator
Biological Process GO:1900378 positive regulation of secondary metabolite biosynthetic process
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 23024348 Reviewed by curator
Biological Process GO:1900232 negative regulation of single-species biofilm formation on inanimate substrate
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 19168621 Reviewed by curator
Molecular Function GO:0008134 transcription factor binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00382
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00072
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0043565 sequence-specific DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02954
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00158
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other PAO1 genes in this class
Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Alginate biosynthesis ECO:0000037
not_recorded
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Two-component System ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.50.2300 - - - 1 140 6.6E-32
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 9 120 2.4E-34
PANTHER PTHR32071 TRANSCRIPTIONAL REGULATORY PROTEIN - - 9 449 0.0
Gene3D G3DSA:1.10.10.60 - - - 407 449 5.0E-8
Pfam PF02954 Bacterial regulatory protein, Fis family IPR002197 DNA binding HTH domain, Fis-type 407 447 3.7E-10
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 11 119 4.4E-29
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 9 192 3.27E-39
Pfam PF00158 Sigma-54 interaction domain IPR002078 RNA polymerase sigma factor 54 interaction domain 149 313 6.7E-63
FunFam G3DSA:3.40.50.300:FF:000006 DNA-binding transcriptional regulator NtrC - - 137 317 9.0E-69
CDD cd00009 AAA - - 152 312 4.51664E-27
Gene3D G3DSA:1.10.8.60 - - - 319 395 5.2E-25
SMART SM00382 AAA_5 IPR003593 AAA+ ATPase domain 167 318 4.6E-7
SUPERFAMILY SSF46689 Homeodomain-like IPR009057 Homeobox-like domain superfamily 360 449 1.31E-8
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 141 318 1.2E-62
Coils Coil Coil - - 119 146 -
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 150 388 1.23E-71
FunFam G3DSA:1.10.8.60:FF:000120 Sigma-54-dependent Fis family transcriptional regulator - - 319 395 4.3E-31

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.