Pseudomonas fluorescens Pf0-1, Pfl01_0623 (gcbA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0052621 diguanylate cyclase activity
IDA
Inferred from Direct Assay 		ECO:0000005
enzyme assay evidence		 21764921 Reviewed by curator
Biological Process GO:2000146 negative regulation of cell motility
IMP
Inferred from Mutant Phenotype 		ECO:0000315
mutant phenotype evidence used in manual assertion		 21764921 Reviewed by curator
Biological Process GO:1900192 positive regulation of single-species biofilm formation
IMP
Inferred from Mutant Phenotype 		ECO:0000315
mutant phenotype evidence used in manual assertion		 21764921 Reviewed by curator
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00072
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 247 378 2.42E-30
Gene3D G3DSA:3.30.70.270 - IPR043128 Reverse transcriptase/Diguanylate cyclase domain 375 543 5.4E-52
Gene3D G3DSA:3.40.50.2300 - - - 242 374 9.9E-28
Gene3D G3DSA:3.40.50.2300 - - - 111 241 2.5E-6
MobiDBLite mobidb-lite consensus disorder prediction - - 527 556 -
CDD cd01949 GGDEF IPR000160 GGDEF domain 378 534 1.57926E-58
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 125 237 0.25
Pfam PF00990 Diguanylate cyclase, GGDEF domain IPR000160 GGDEF domain 378 532 1.2E-39
NCBIfam TIGR00254 JCVI: diguanylate cyclase (GGDEF) domain IPR000160 GGDEF domain 373 535 7.1E-45
CDD cd00156 REC - - 252 352 8.07722E-24
FunFam G3DSA:3.30.70.270:FF:000001 Diguanylate cyclase domain protein - - 371 537 6.3E-49
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 249 362 3.3E-27
FunFam G3DSA:3.40.50.2300:FF:000346 Diguanylate cyclase response regulator - - 246 374 1.3E-56
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 251 362 9.6E-22
PANTHER PTHR45138 REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM - - 91 538 1.5E-87
SUPERFAMILY SSF55073 Nucleotide cyclase IPR029787 Nucleotide cyclase 381 536 1.33E-46
MobiDBLite mobidb-lite consensus disorder prediction - - 536 556 -
SMART SM00267 duf1_3 IPR000160 GGDEF domain 365 536 8.4E-52

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.