Pseudomonas aeruginosa UCBPP-PA14, PA14_00290 (aroE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0050661 NADP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00507
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004764 shikimate 3-dehydrogenase (NADP+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00507
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00507
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019632 shikimate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00507
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00400 Phenylalanine, tyrosine and tryptophan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. IPR022893 Shikimate dehydrogenase family 1 270 31.372
SUPERFAMILY SSF53223 1 100 1.09E-30
Pfam PF01488 Shikimate / quinate 5-dehydrogenase IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase 116 165 4.0E-7
TIGRFAM TIGR00507 aroE: shikimate dehydrogenase IPR011342 Shikimate dehydrogenase 4 271 5.8E-76
CDD cd01065 NAD_bind_Shikimate_DH 100 255 1.22349E-40
Pfam PF18317 Shikimate 5'-dehydrogenase C-terminal domain IPR041121 SDH, C-terminal 238 268 9.0E-11
Pfam PF08501 Shikimate dehydrogenase substrate binding domain IPR013708 Shikimate dehydrogenase substrate binding, N-terminal 6 87 5.1E-24
Gene3D G3DSA:3.40.50.720 115 237 2.5E-85
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 101 270 1.21E-36
Gene3D G3DSA:3.40.50.10860 6 258 2.5E-85

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.