Pseudomonas aeruginosa UCBPP-PA14, PA14_00450 (trpB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006568 tryptophan metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00168
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000162 tryptophan biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF001413
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004834 tryptophan synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF001413
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00400 Phenylalanine, tyrosine and tryptophan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PIRSF PIRSF001413 IPR023026 Tryptophan synthase beta chain/beta chain-like 4 402 0.0
ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. IPR006653 Tryptophan synthase, beta chain, conserved site 86 100 -
Gene3D G3DSA:3.40.50.1100 59 389 0.0
SUPERFAMILY SSF53686 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme 8 394 0.0
Gene3D G3DSA:3.40.50.1100 15 211 0.0
Hamap MF_00133 Tryptophan synthase beta chain [trpB]. IPR023026 Tryptophan synthase beta chain/beta chain-like 7 396 52.614
TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit IPR006654 Tryptophan synthase, beta chain 12 395 0.0
Pfam PF00291 Pyridoxal-phosphate dependent enzyme IPR001926 Pyridoxal-phosphate dependent enzyme 58 383 2.8E-45
CDD cd06446 Trp-synth_B IPR006654 Tryptophan synthase, beta chain 32 392 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.