Pseudomonas aeruginosa UCBPP-PA14, PA14_00560 (exoT)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005576 extracellular region
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03496
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005096 GTPase activator activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01372
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009405 pathogenesis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03496
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Secreted Factors (toxins, enzymes, alginate) Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Type III secretion ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR01372 Yersinia virulence determinant YopE protein signature IPR003537 Yersinia virulence determinant YopE 215 232 8.9E-28
PRINTS PR01372 Yersinia virulence determinant YopE protein signature IPR003537 Yersinia virulence determinant YopE 132 149 8.9E-28
PRINTS PR01372 Yersinia virulence determinant YopE protein signature IPR003537 Yersinia virulence determinant YopE 181 199 8.9E-28
CDD cd00219 ToxGAP IPR014773 Virulence factor YopE, GAP domain 108 227 1.01989E-53
Pfam PF03545 Yersinia virulence determinant (YopE) IPR014773 Virulence factor YopE, GAP domain 132 201 4.2E-34
SUPERFAMILY SSF56399 230 427 2.06E-33
Pfam PF03496 ADP-ribosyltransferase exoenzyme IPR003540 ADP ribosyltransferase 246 432 3.6E-31
Gene3D G3DSA:3.90.176.10 241 410 1.9E-23
PRINTS PR01372 Yersinia virulence determinant YopE protein signature IPR003537 Yersinia virulence determinant YopE 23 36 8.9E-28
Gene3D G3DSA:1.20.120.260 IPR037168 Virulence factor YopE, GAP domain superfamily 114 240 1.4E-46
PRINTS PR01372 Yersinia virulence determinant YopE protein signature IPR003537 Yersinia virulence determinant YopE 39 56 8.9E-28
SUPERFAMILY SSF47233 IPR037168 Virulence factor YopE, GAP domain superfamily 100 231 1.83E-51

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.