Pseudomonas aeruginosa UCBPP-PA14, PA14_17500 (mutS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF05188
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0140664 ATP-dependent DNA damage sensor activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR11361
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030983 mismatched DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF05188
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006298 mismatch repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF05188
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau03430 Mismatch repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF05188 MutS domain II IPR007860 DNA mismatch repair protein MutS, connector domain 128 253 4.6E-31
PIRSF PIRSF037677 Msh6 IPR017261 DNA mismatch repair protein MutS/MSH 200 833 7.1E-124
Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. IPR005748 DNA mismatch repair protein MutS 7 847 25.302929
SMART SM00533 DNAend IPR007696 DNA mismatch repair protein MutS, core 283 590 6.2E-109
PANTHER PTHR11361 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER IPR045076 DNA mismatch repair MutS family 11 800 0.0
Gene3D G3DSA:1.10.1420.10 - - - 265 559 3.7E-111
MobiDBLite mobidb-lite consensus disorder prediction - - 796 816 -
Gene3D G3DSA:3.30.420.110 MutS, connector domain IPR036678 MutS, connector domain superfamily 127 260 4.0E-43
PIRSF PIRSF037677 Msh6 IPR017261 DNA mismatch repair protein MutS/MSH 2 180 2.7E-27
Coils Coil Coil - - 513 533 -
NCBIfam TIGR01070 JCVI: DNA mismatch repair protein MutS IPR005748 DNA mismatch repair protein MutS 7 852 0.0
FunFam G3DSA:3.40.50.300:FF:000283 DNA mismatch repair protein MutS - - 566 820 8.2E-129
SUPERFAMILY SSF55271 DNA repair protein MutS, domain I IPR016151 DNA mismatch repair protein MutS, N-terminal 3 115 6.28E-43
Pfam PF00488 MutS domain V IPR000432 DNA mismatch repair protein MutS, C-terminal 609 795 7.8E-86
FunFam G3DSA:3.40.1170.10:FF:000001 DNA mismatch repair protein MutS - - 1 121 4.5E-58
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 568 795 8.1E-59
Gene3D G3DSA:3.40.1170.10 DNA repair protein MutS, domain I IPR016151 DNA mismatch repair protein MutS, N-terminal 1 121 5.8E-47
Pfam PF05190 MutS family domain IV IPR007861 DNA mismatch repair protein MutS, clamp 427 517 5.3E-28
FunFam G3DSA:1.10.1420.10:FF:000002 DNA mismatch repair protein MutS - - 386 502 3.7E-48
SUPERFAMILY SSF48334 DNA repair protein MutS, domain III IPR036187 DNA mismatch repair protein MutS, core domain superfamily 267 564 7.06E-85
SMART SM00534 mutATP5 IPR000432 DNA mismatch repair protein MutS, C-terminal 606 792 1.1E-121
FunFam G3DSA:3.30.420.110:FF:000001 DNA mismatch repair protein MutS - - 127 262 4.4E-62
CDD cd03284 ABC_MutS1 - - 578 791 1.15382E-127
SUPERFAMILY SSF53150 DNA repair protein MutS, domain II IPR036678 MutS, connector domain superfamily 114 266 9.16E-44
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 567 823 3.0E-101
Pfam PF05192 MutS domain III IPR007696 DNA mismatch repair protein MutS, core 270 558 1.9E-38
Gene3D G3DSA:6.10.140.430 - - - 825 853 8.6E-11
Gene3D G3DSA:1.10.1420.10 - - - 386 502 3.7E-111
Pfam PF01624 MutS domain I IPR007695 DNA mismatch repair protein MutS-like, N-terminal 8 119 1.9E-41
MobiDBLite mobidb-lite consensus disorder prediction - - 799 815 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.