Pseudomonas aeruginosa UCBPP-PA14, PA14_19050 (metG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006431 methionyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00398
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF09334
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00398
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF09334
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00398
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000049 tRNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01588
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004825 methionine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00398
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class
Translation, post-translational modification, degradation Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00450 Selenocompound metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR00399 JCVI: methionine--tRNA ligase subunit beta IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal 542 678 7.0E-40
CDD cd00814 MetRS_core IPR033911 Methioninyl-tRNA synthetase core domain 6 370 0.0
Gene3D G3DSA:2.20.28.20 - IPR029038 Methionyl-tRNA synthetase, Zn-domain 141 175 0.0
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 41 55 2.2E-24
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 290 305 2.2E-24
Pfam PF09334 tRNA synthetases class I (M) IPR015413 Methionyl/Leucyl tRNA synthetase 7 395 0.0
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 569 678 1.3E-32
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 383 394 2.2E-24
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 250 261 2.2E-24
Hamap MF_00098 Methionine--tRNA ligase [metG]. IPR023458 Methionine-tRNA ligase, type 1 5 545 39.358952
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 9 22 2.2E-24
NCBIfam TIGR00398 JCVI: methionine--tRNA ligase IPR014758 Methionyl-tRNA synthetase 7 535 0.0
FunFam G3DSA:2.20.28.20:FF:000001 Methionine--tRNA ligase - - 141 175 8.8E-16
PANTHER PTHR45765 METHIONINE--TRNA LIGASE IPR023458 Methionine-tRNA ligase, type 1 3 676 0.0
Pfam PF01588 Putative tRNA binding domain IPR002547 tRNA-binding domain 582 675 3.6E-20
SUPERFAMILY SSF57770 Methionyl-tRNA synthetase (MetRS), Zn-domain IPR029038 Methionyl-tRNA synthetase, Zn-domain 141 175 5.36E-12
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 7 383 0.0
CDD cd02800 tRNA_bind_EcMetRS_like IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal 572 678 1.95481E-42
Pfam PF19303 Anticodon binding domain of methionyl tRNA ligase IPR041872 Methionyl-tRNA synthetase, anticodon-binding domain 416 516 4.5E-7
FunFam G3DSA:2.40.50.140:FF:000042 Methionine--tRNA ligase - - 568 678 8.6E-43
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 89 100 2.2E-24
SUPERFAMILY SSF52374 Nucleotidylyl transferase - - 4 386 1.13E-98
SUPERFAMILY SSF47323 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding 389 547 1.42E-42
CDD cd07957 Anticodon_Ia_Met IPR041872 Methionyl-tRNA synthetase, anticodon-binding domain 373 505 6.7692E-37
Gene3D G3DSA:1.10.730.10 - - - 388 526 2.4E-36
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 571 677 1.64E-26
FunFam G3DSA:1.10.730.10:FF:000005 Methionine--tRNA ligase - - 388 526 4.0E-57

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.