Pseudomonas aeruginosa UCBPP-PA14, PA14_19620 (folX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006729 tetrahydrobiopterin biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA3439
 ECO:0000249
sequence similarity evidence used in automatic assertion		 19897652
Biological Process GO:0006760 folic acid-containing compound metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02152
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004150 dihydroneopterin aldolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02152
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF55620 Tetrahydrobiopterin biosynthesis enzymes-like - - 7 120 2.48E-30
Pfam PF02152 Dihydroneopterin aldolase IPR006157 Dihydroneopterin aldolase/epimerase domain 11 119 2.5E-25
Gene3D G3DSA:3.30.1130.10 - IPR043133 GTP cyclohydrolase I, C-terminal/NADPH-dependent 7-cyano-7-deazaguanine reductase 6 122 3.8E-33
PANTHER PTHR42844 DIHYDRONEOPTERIN ALDOLASE 1-RELATED IPR006156 Dihydroneopterin aldolase 6 120 1.5E-22
SMART SM00905 FolB_2 IPR006157 Dihydroneopterin aldolase/epimerase domain 11 121 1.1E-32
NCBIfam TIGR00526 JCVI: FolB domain IPR006157 Dihydroneopterin aldolase/epimerase domain 8 119 5.1E-31
CDD cd00534 DHNA_DHNTPE IPR006157 Dihydroneopterin aldolase/epimerase domain 8 119 1.14958E-30
FunFam G3DSA:3.30.1130.10:FF:000005 D-erythro-7,8-dihydroneopterin triphosphate epimerase - - 4 123 1.1E-62

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.